DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32755 and cfi

DIOPT Version :9

Sequence 1:	NP_727055.1	Gene:	CG32755 / 318192	FlyBaseID:	FBgn0052755	Length:	315	Species:	Drosophila melanogaster
Sequence 2:	NP_001027508.1	Gene:	cfi / 613100	XenbaseID:	XB-GENE-5953276	Length:	602	Species:	Xenopus tropicalis

Alignment Length:	273	Identity:	84/273 - (30%)
Similarity:	125/273 - (45%)	Gaps:	56/273 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 PTATASPFVILPKIVGGYTVTIDQVPFQVSVRRRSIHERHYGLGHVCGGAVISQRVVCSAAHCYA 89
            |.|..:......:::||.....:|.|:||:::.        |....|||..|....|.:||||..
Frog   346 PPAAPTKITRKKRVIGGTNAVKNQFPWQVAIKD--------GTSVNCGGIYIGGCWVLTAAHCVR 402

  Fly    90 INTSVPLVYRDPELYVVVAGSSAIDRT--DRFTQEYLVQRIVGHKDYNGSTLENDIALLFLNGF- 151
            .|        .|:.|:::.  ..:||.  |:....:.|:.::.|:.||.:|.|||||||.:...
Frog   403 AN--------QPQRYLIIL--ELLDRLSYDKDIDSFPVKSVIVHESYNPNTYENDIALLEVKNIY 457

  Fly   152 ----------------IPWESPGVRAIPLAIKAPEEGTTCLIHGWGKVTMKEKSASLQQAPVPIL 200
                            :||.       |...:|   |.||.:.|||:.....:...|:...:.::
Frog   458 SNPKCMQTDNNMVPACVPWS-------PFQFRA---GDTCTVSGWGREKGMSRVFHLKWGHINLM 512

  Fly   201 NKELCQVIYK--LPASQMCAGFLQGGIDACQGDSGGPLIC-----DGRLAGIISWGVGCADPGYP 258
            |.  |..:||  ......|||...|.||||:|||||||:|     ...:.||:|||..|..||:|
Frog   513 NN--CSEVYKERFLDKMECAGTYDGSIDACKGDSGGPLVCYDVNNVAYVWGIVSWGENCGVPGFP 575

  Fly   259 GVYTNVSHFLKWI 271
            ||||.|:|:.:||
Frog   576 GVYTKVAHYYEWI 588

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32755	NP_727055.1	Tryp_SPc	37..271	CDD:214473	80/259 (31%)
CG32755	NP_727055.1	Tryp_SPc	38..273	CDD:238113	82/260 (32%)
cfi	NP_001027508.1	FIMAC	41..110	CDD:214493
		SR	114..202	CDD:214555
		LDLa	222..256	CDD:238060
		LDLa	259..292	CDD:238060
		Tryp_SPc	359..589	CDD:238113	82/260 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000