DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG32755 and F12

DIOPT Version :9

Sequence 1:	NP_727055.1	Gene:	CG32755 / 318192	FlyBaseID:	FBgn0052755	Length:	315	Species:	Drosophila melanogaster
Sequence 2:	NP_067464.2	Gene:	F12 / 58992	MGIID:	1891012	Length:	597	Species:	Mus musculus

Alignment Length:	268	Identity:	88/268 - (32%)
Similarity:	128/268 - (47%)	Gaps:	51/268 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 KIVGGYTVTIDQVPFQVSVRRRSIHERHYGLGHVCGGAVISQRVVCSAAHCYAINTSVPLVYRDP 101
            ::|||........|:..::         |...:.|.|::|:...|.:||||.....:       |
Mouse   354 RVVGGLVALPGSHPYIAAL---------YWGNNFCAGSLIAPCWVLTAAHCLQNRPA-------P 402

  Fly   102 ELYVVVAGSSAIDRTDRFTQEYLVQRIVGHKDYNGSTLENDIALLFLNGFIPWE---------SP 157
            |...||.|....:::..:.|...|:....|:.::..|.::|:|||.|.     |         ||
Mouse   403 EELTVVLGQDRHNQSCEWCQTLAVRSYRLHEGFSSITYQHDLALLRLQ-----ESKTNSCAILSP 462

  Fly   158 GVR--AIPLAIKAPEEGTTCLIHGWGK--VTMKEKSASLQQAPVPILNKELC-------QVIYKL 211
            .|:  .:|.....|.|...|.:.|||.  ...:|.|..||:|.||.:..:.|       ..|  |
Mouse   463 HVQPVCLPSGAAPPSETVLCEVAGWGHQFEGAEEYSTFLQEAQVPFIALDRCSNSNVHGDAI--L 525

  Fly   212 PASQMCAGFLQGGIDACQGDSGGPLICDG-------RLAGIISWGVGCADPGYPGVYTNVSHFLK 269
            | ..:|||||:||.|||||||||||:|:.       .|.|:||||.||.|...|||||:|:::|.
Mouse   526 P-GMLCAGFLEGGTDACQGDSGGPLVCEEGTAEHQLTLRGVISWGSGCGDRNKPGVYTDVANYLA 589

  Fly   270 WIRRANAS 277
            ||::..||
Mouse   590 WIQKHIAS 597

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32755	NP_727055.1	Tryp_SPc	37..271	CDD:214473	84/260 (32%)
CG32755	NP_727055.1	Tryp_SPc	38..273	CDD:238113	86/261 (33%)
F12	NP_067464.2	FN2	41..88	CDD:238019
		EGF_CA	96..131	CDD:238011
		FN1	133..173	CDD:238018
		EGF	178..206	CDD:278437
		KR	217..295	CDD:294073
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	306..338
		Tryp_SPc	354..591	CDD:214473	84/260 (32%)
		Tryp_SPc	355..594	CDD:238113	86/262 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910