DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32755 and tmprss5

DIOPT Version :9

Sequence 1:	NP_727055.1	Gene:	CG32755 / 318192	FlyBaseID:	FBgn0052755	Length:	315	Species:	Drosophila melanogaster
Sequence 2:	XP_009289870.1	Gene:	tmprss5 / 569688	ZFINID:	ZDB-GENE-131121-184	Length:	551	Species:	Danio rerio

Alignment Length:	260	Identity:	96/260 - (36%)
Similarity:	154/260 - (59%)	Gaps:	47/260 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 LPKIVGGYTVTIDQVPFQVSVRRRSIHERHYGLGHVCGGAVISQRVVCSAAHCYAINTSVPLVYR 99
            ||:|:||....:.:.|:|||:        :|...|:|||::|:.:.:.:||||  ::.     ||
Zfish   309 LPRIIGGVEAALGRWPWQVSL--------YYNNRHICGGSIITNQWIVTAAHC--VHN-----YR 358

  Fly   100 DPEL--YVVVAG--SSAIDRTDRFTQEYLVQRIVGHKDYNGSTLENDIALLFLNGFIPWESPGVR 160
            .|::  :||.||  :|.:.:..:: |.:.|:||:.:|:||..|.:|||||:.|...:.: |..:|
Zfish   359 LPQVPSWVVYAGIITSNLAKLAQY-QGFAVERIIYNKNYNHRTHDNDIALVKLKTPLNF-SDTIR 421

  Fly   161 AIPLAIKAPE------EGTTCLIHGWG-----KVTMKEKSASLQQAPVPILNKELC--QVIY--K 210
            .:.|    |:      .||.|.|.|||     .|.:.|   .|::||||:::.:.|  ..:|  :
Zfish   422 PVCL----PQYDHDLPGGTQCWISGWGYTQPDDVLIPE---VLKEAPVPLISTKKCNSSCMYNGE 479

  Fly   211 LPASQMCAGFLQGGIDACQGDSGGPLICDG----RLAGIISWGVGCADPGYPGVYTNVSHFLKWI 271
            :.:..:|||:.:|.:|||||||||||:|..    ||.|::|||.|||:|.:||||:.|:.||.||
Zfish   480 ITSRMLCAGYSEGKVDACQGDSGGPLVCQDENVWRLVGVVSWGTGCAEPNHPGVYSKVAEFLGWI 544

Fly 272 271
Zfish 545 544

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32755	NP_727055.1	Tryp_SPc	37..271	CDD:214473	92/256 (36%)
CG32755	NP_727055.1	Tryp_SPc	38..273	CDD:238113	94/257 (37%)
tmprss5	XP_009289870.1	SRCR_2	211..306	CDD:292133
		Tryp_SPc	311..544	CDD:214473	92/256 (36%)
		Tryp_SPc	312..547	CDD:238113	94/257 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24253
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	3.010