DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32755 and prss27

DIOPT Version :9

Sequence 1:	NP_727055.1	Gene:	CG32755 / 318192	FlyBaseID:	FBgn0052755	Length:	315	Species:	Drosophila melanogaster
Sequence 2:	XP_031749235.1	Gene:	prss27 / 496619	XenbaseID:	XB-GENE-5744470	Length:	724	Species:	Xenopus tropicalis

Alignment Length:	367	Identity:	105/367 - (28%)
Similarity:	155/367 - (42%)	Gaps:	86/367 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 WMCLLIVATHSGITQSQIGQPTATA--------SPFVIL-------------------------P 36
            |:|.|....|....:.|...|:.|.        .|.::|                         .
Frog   354 WLCALHKQYHFSRAEGQKSLPSVTQLSLIGPMDPPSMMLRIISLLLAGFAVTAISTGCGQPAFSD 418

  Fly    37 KIVGGYTVTIDQVPFQVSVRRRSIHERHYGLGHVCGGAVISQRVVCSAAHCYAINTSVPLVYRDP 101
            :||||......:.|:|||:        .|...|:|||:::|...|.|||||:      |..|:..
Frog   419 RIVGGNNAVFGEWPWQVSI--------VYQNSHICGGSLVSSNWVVSAAHCF------PRSYKIE 469

  Fly   102 ELYVVVAGSSAIDRTDRFTQEYLVQRIVGHKDYNGSTLENDIALLFLNGFIPWESPGVRAIPLAI 166
            .:.|:: |..|:...........|:|::.:..|.|.....|||::.:...:.:.|   ..:|:.|
Frog   470 NMQVLL-GCFALMNLTSDAVIIRVKRVITYPLYTGEGSSGDIAMVEMESPVTYSS---YILPICI 530

  Fly   167 KAPEE----GTTCLIHGWGKVTMKEKSAS----LQQAPVPILNKELCQVIYKL-----PASQM-- 216
            ....|    |..|.:.|||.: ..:.|.|    ||:..||::|...|..:|..     ||:|:
Frog   531 PLTNEDFPSGKMCWVTGWGNI-QSDVSLSPPYPLQEVEVPLVNASSCDTMYHYNSDLNPATQLVH 594

  Fly   217 ----CAGFLQGGIDACQGDSGGPLICDGR----LAGIISWGVGCADPGYPGVYTNVSHFLKWIRR 273
                |||:.:|..|||||||||||.|...    |.||:|||.|||.|..|||||.||.|..||.:
Frog   595 DDMICAGYPEGQKDACQGDSGGPLACKSGNYWFLTGIVSWGDGCAQPNRPGVYTKVSSFSSWINQ 659

  Fly   274 ---ANASLDYSEYRQIPPLNLASRRSV--------SSSCLGI 304
               .|.|:.......|...|.:|.:..        |::.:|:
Frog   660 YLVLNVSVTTKTPHSISLANSSSTKEAVTNTDYKNSNNSVGL 701

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32755	NP_727055.1	Tryp_SPc	37..271	CDD:214473	87/256 (34%)
CG32755	NP_727055.1	Tryp_SPc	38..273	CDD:238113	89/257 (35%)
prss27	XP_031749235.1	Tryp_SPc	34..271	CDD:238113
prss27	XP_031749235.1	Tryp_SPc	420..659	CDD:238113	89/257 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910