DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32755 and ea

DIOPT Version :9

Sequence 1:	NP_727055.1	Gene:	CG32755 / 318192	FlyBaseID:	FBgn0052755	Length:	315	Species:	Drosophila melanogaster
Sequence 2:	NP_524362.2	Gene:	ea / 41858	FlyBaseID:	FBgn0000533	Length:	392	Species:	Drosophila melanogaster

Alignment Length:	296	Identity:	95/296 - (32%)
Similarity:	140/296 - (47%)	Gaps:	60/296 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 QPTATASPFVILP---------KIVGGYTVTIDQVPFQVSVRRRSIHERHYG-LGHVCGGAVISQ 78
            :|..|::..:.||         :|.||....||:.|:...:.    :.:..| .||.|||::||.
  Fly   105 KPNVTSNSLLPLPGQCGNILSNRIYGGMKTKIDEFPWMALIE----YTKSQGKKGHHCGGSLIST 165

  Fly    79 RVVCSAAHCYAIN-TSVPLVYR-------------DPELYVVVAG--SSAIDRTDRFTQEYLVQR 127
            |.|.:|:||  :| .::|..:|             :|:..|.|.|  ..|....|     ..|:|
  Fly   166 RYVITASHC--VNGKALPTDWRLSGVRLGEWDTNTNPDCEVDVRGMKDCAPPHLD-----VPVER 223

  Fly   128 IVGHKDYNGSTLE--NDIALLFLNGFIPWESPGVRAI--PLAI---KAPEEGTTCLIHGWGKVTM 185
            .:.|.||..::..  ||||||.|...:.: :..||.|  ||.:   .|..:|.|..:.||||...
  Fly   224 TIPHPDYIPASKNQVNDIALLRLAQQVEY-TDFVRPICLPLDVNLRSATFDGITMDVAGWGKTEQ 287

  Fly   186 KEKSASLQQAPVPILNKELCQVIYK-----LPASQMCAGFLQGGIDACQGDSGGPLI-CDGR--- 241
            ...|....:|.|.....:.||.:|.     |..:|||||..: |:|:|:|||||||| .|..
  Fly   288 LSASNLKLKAAVEGFRMDECQNVYSSQDILLEDTQMCAGGKE-GVDSCRGDSGGPLIGLDTNKVN 351

  Fly   242 ----LAGIISWG-VGCADPGYPGVYTNVSHFLKWIR 272
                |||::|:| ..|...|:|||||.|..::.||:
  Fly   352 TYYFLAGVVSFGPTPCGLAGWPGVYTLVGKYVDWIQ 387

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32755	NP_727055.1	Tryp_SPc	37..271	CDD:214473	89/271 (33%)
CG32755	NP_727055.1	Tryp_SPc	38..273	CDD:238113	91/273 (33%)
ea	NP_524362.2	CLIP	37..89	CDD:288855
		Tryp_SPc	127..386	CDD:214473	89/271 (33%)
		Tryp_SPc	128..389	CDD:238113	91/273 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.910