Protein Alignment CG32755 and KLKB1

DIOPT Version :10

• Sequence 1: NP_727055.1
• Gene: CG32755 / 318192
• FlyBaseID: FBgn0052755
• Length: 315
• Species: Drosophila melanogaster
• Sequence 2: XP_011530232.1
• Gene: KLKB1 / 3818
• HGNCID: 6371
• Length: 649
• Species: Homo sapiens
• Alignment Length: 272
• Identity: 96/272 - (35%)
• Similarity: 142/272 - (52%)
• Gaps: 45/272 - (16%)

  Fly    37 KIVGGYTVTIDQVPFQVSVRRRSIHERHYGLGHVCGGAVISQRVVCSAAHCYAINTSVPL--VYR 99
            :||||...:..:.|:|||::.:...:|     |:|||::|..:.|.:||||:   ..:||  |:|
Human   401 RIVGGTNSSWGEWPWQVSLQVKLTAQR-----HLCGGSLIGHQWVLTAAHCF---DGLPLQDVWR 457

  Fly   100 DPELYVVVAGSSAIDRTDRFTQEYLVQRIVGHKDYNGSTLENDIALLFLN---GFIPWESPGVRA 161
               :|..:...|.|.:...|:|   ::.|:.|::|..|...:||||:.|.   .:..::.|
Human   458 ---IYSGILNLSDITKDTPFSQ---IKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKP---- 512

  Fly   162 IPLAIKAPEEG------TTCLIHGWGKVTMKEKSA---SLQQAPVPILNKELCQ---VIYKLPAS 214
                |..|.:|      |.|.:.|||  ..|||..   .||:..:|::..|.||   ..||:...
Human   513 ----ICLPSKGDTSTIYTNCWVTGWG--FSKEKGEIQNILQKVNIPLVTNEECQKRYQDYKITQR 571

  Fly   215 QMCAGFLQGGIDACQGDSGGPLIC--DG--RLAGIISWGVGCADPGYPGVYTNVSHFLKWIRRAN 275
            .:|||:.:||.|||:|||||||:|  :|  ||.||.|||.|||....|||||.|:.::.||....
Human   572 MVCAGYKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVAEYMDWILEKT 636

  Fly   276 ASLDYSEYRQIP 287
            .|.|.....|.|
Human   637 QSSDGKAQMQSP 648

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG32755	NP_727055.1	Tryp_SPc	38..273	CDD:238113	92/255 (36%)
KLKB1	XP_011530232.1	APPLE	21..104	CDD:128519
		APPLE	111..194	CDD:128519
		APPLE	212..295	CDD:128519
		APPLE	303..386	CDD:128519
		Tryp_SPc	402..632	CDD:238113	90/253 (36%)