Protein Alignment CG32755 and KLK2

DIOPT Version :10

• Sequence 1: NP_727055.1
• Gene: CG32755 / 318192
• FlyBaseID: FBgn0052755
• Length: 315
• Species: Drosophila melanogaster
• Sequence 2: NP_005542.1
• Gene: KLK2 / 3817
• HGNCID: 6363
• Length: 261
• Species: Homo sapiens
• Alignment Length: 295
• Identity: 96/295 - (32%)
• Similarity: 133/295 - (45%)
• Gaps: 67/295 - (22%)

  Fly     4 LWMCLLIVATHSGITQSQIGQPTATASPFVILPKIVGGYTVTIDQVPFQVSVRRRSIHERHYGLG 68
            :|..:|.:|...|.|         .|.| :|..:||||:.......|:||:|       ..:|..
Human     1 MWDLVLSIALSVGCT---------GAVP-LIQSRIVGGWECEKHSQPWQVAV-------YSHGWA 48

  Fly    69 HVCGGAVISQRVVCSAAHCYAINTSVPLVYRDPELYVVVAGSSAIDRTDRFTQEYLVQRI----- 128
            | |||.::..:.|.:||||...|:.|.|                 .|.:.|..|...||:
Human    49 H-CGGVLVHPQWVLTAAHCLKKNSQVWL-----------------GRHNLFEPEDTGQRVPVSHS 95

  Fly   129 VGHKDYNGSTLE-----------NDIALLFLNGFIPWESPG-----VRAIPLAIKAPEEGTTCLI 177
            ..|..||.|.|:           :|:.||.|:      .|.     |:.:.|..:.|..||||..
Human    96 FPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLS------EPAKITDVVKVLGLPTQEPALGTTCYA 154

  Fly   178 HGWGKVTMKE--KSASLQQAPVPILNKELCQVIY--KLPASQMCAGFLQGGIDACQGDSGGPLIC 238
            .|||.:..:|  :..|||...:.:|:.::|...|  |:....:|||...||.|.|.|||||||:|
Human   155 SGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFMLCAGLWTGGKDTCGGDSGGPLVC 219

  Fly   239 DGRLAGIISWG-VGCADPGYPGVYTNVSHFLKWIR 272
            :|.|.||.||| ..||.|..|.|||.|.|:.|||:
Human   220 NGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIK 254

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG32755	NP_727055.1	Tryp_SPc	38..273	CDD:238113	88/261 (34%)
KLK2	NP_005542.1	Tryp_SPc	25..256	CDD:238113	88/261 (34%)