DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32755 and Tmprss4

DIOPT Version :9

Sequence 1:	NP_727055.1	Gene:	CG32755 / 318192	FlyBaseID:	FBgn0052755	Length:	315	Species:	Drosophila melanogaster
Sequence 2:	XP_038937788.1	Gene:	Tmprss4 / 367074	RGDID:	1305033	Length:	478	Species:	Rattus norvegicus

Alignment Length:	295	Identity:	94/295 - (31%)
Similarity:	134/295 - (45%)	Gaps:	46/295 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 LLI--VATHSGITQSQIGQPTATASPFVIL-----------PKIVGGYTVTIDQVPFQVSVRRRS 59
            ||:  |..:|...|.|.|..:..:...|.|           .::|||...:.|..|:|||::
  Rat   203 LLVTPVTGNSQELQMQNGSRSCLSGSLVSLRCLDCGKSLKTTRVVGGVEASADSWPWQVSIQ--- 264

  Fly    60 IHERHYGLGHVCGGAVISQRVVCSAAHCYAINTSVPLVYRDPELYVVVAGSSAIDRTDRFTQEYL 124
                 |...|||||:::....:.:||||:.       .|.|...:.|.|||:.:..:....
  Rat   265 -----YNKQHVCGGSILDHHWILTAAHCFR-------KYLDVSSWKVRAGSNKLGNSPSLP---- 313

  Fly   125 VQRIVGHKDYNGSTLENDIALLFLNGFIPWESPG-VRAIPLAIKAPEEGTT--CLIHGWG--KVT 184
            |.:|...:.......|.||||:.|.  :|....| ||.|.|.....|...|  ..:.|||  :..
  Rat   314 VAKIFIAEPNPLQPKEKDIALVKLK--MPLTFSGSVRPICLPFSDEELIPTMPVWVIGWGFTEEN 376

  Fly   185 MKEKSASLQQAPVPILNKELCQV--IY--KLPASQMCAGFLQGGIDACQGDSGGPLIC---DGRL 242
            ..:.|.:|.||.|.:::...|..  .|  ::.|..:|||..|||.|.|||||||||:.   ..::
  Rat   377 GGKMSDTLLQASVQVIDSARCNAEDAYQGEVTAGMLCAGTPQGGKDTCQGDSGGPLMYHYDKWQV 441

  Fly   243 AGIISWGVGCADPGYPGVYTNVSHFLKWIRRANAS 277
            .||:|||.||..|..|||||.|:.:|.||.....|
  Rat   442 VGIVSWGYGCGSPSTPGVYTKVTAYLDWIYNVRRS 476

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32755	NP_727055.1	Tryp_SPc	37..271	CDD:214473	82/245 (33%)
CG32755	NP_727055.1	Tryp_SPc	38..273	CDD:238113	84/246 (34%)
Tmprss4	XP_038937788.1	LDLa	99..133	CDD:238060
		SRCR_2	149..238	CDD:413346	9/34 (26%)
		Tryp_SPc	245..470	CDD:214473	82/245 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910