DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32755 and Corin

DIOPT Version :9

Sequence 1:	NP_727055.1	Gene:	CG32755 / 318192	FlyBaseID:	FBgn0052755	Length:	315	Species:	Drosophila melanogaster
Sequence 2:	NP_610297.2	Gene:	Corin / 35691	FlyBaseID:	FBgn0033192	Length:	1397	Species:	Drosophila melanogaster

Alignment Length:	264	Identity:	86/264 - (32%)
Similarity:	129/264 - (48%)	Gaps:	50/264 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 KIVGGYTVTIDQVPFQVSVRRRSIHERHYGLG-----HVCGGAVISQRVVCSAAHCYAINTSVPL 96
            :|:||...:....||..::           ||     ..|.|.:||.:.|.:|:||.. |.||
  Fly  1103 RIIGGTQASPGNWPFLAAI-----------LGGPEKIFYCAGVLISDQWVLTASHCVG-NYSV-- 1153

  Fly    97 VYRDPELYVVVAGSSAIDRTDRFT---QEYLVQRIVGHKDYNGSTL-ENDIALLFLNGFIPWESP 157
              .|.|.:.:..|   :.|.:.||   |:..|:.::.|..||.:.. :|||||..|...:.:..
  Fly  1154 --IDLEDWTIQLG---VTRRNSFTYSGQKVKVKAVIPHPQYNMAIAHDNDIALFQLATRVAFHE- 1212

  Fly   158 GVRAIPLAIKAP-----EEGTTCLIHGWGKVTMKEKSAS----LQQAPVPILNKELC-QVIYKLP 212
              ..:|:.:..|     ..||.|.:.||||...|:..::    :.:..|||:.:..| :.:..|.
  Fly  1213 --HLLPVCLPPPSVRNLHPGTLCTVIGWGKREDKDPKSTYEYIVNEVQVPIITRNQCDEWLDNLT 1275

  Fly   213 ASQ--MCAGFLQGGIDACQGDSGGPLIC--DGR-----LAGIISWGVGCADPGYPGVYTNVSHFL 268
            .|:  :||||..||.|||||||||||:|  .|.     :.||:|||:.||.|..||||.||..::
  Fly  1276 VSEGMVCAGFDDGGKDACQGDSGGPLLCPYPGEKNRWFVGGIVSWGIMCAHPRLPGVYANVVQYV 1340

  Fly   269 KWIR 272
            .||:
  Fly  1341 PWIQ 1344

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32755	NP_727055.1	Tryp_SPc	37..271	CDD:214473	84/261 (32%)
CG32755	NP_727055.1	Tryp_SPc	38..273	CDD:238113	86/263 (33%)
Corin	NP_610297.2	CRD_FZ	778..894	CDD:143549
		LDLa	911..942	CDD:238060
		LDLa	945..979	CDD:238060
		SR	980..>1034	CDD:214555
		SRCR	992..1086	CDD:278931
		Tryp_SPc	1103..1343	CDD:214473	84/261 (32%)
		Tryp_SPc	1104..1346	CDD:238113	86/263 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24253
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.010