Protein Alignment CG32755 and KLK3

DIOPT Version :10

• Sequence 1: NP_727055.1
• Gene: CG32755 / 318192
• FlyBaseID: FBgn0052755
• Length: 315
• Species: Drosophila melanogaster
• Sequence 2: NP_001639.1
• Gene: KLK3 / 354
• HGNCID: 6364
• Length: 261
• Species: Homo sapiens
• Alignment Length: 286
• Identity: 89/286 - (31%)
• Similarity: 137/286 - (47%)
• Gaps: 49/286 - (17%)

  Fly     4 LWMCLLIVATHSGITQSQIGQPTATASPFVILPKIVGGYTVTIDQVPFQVSVRRRSIHERHYGLG 68
            :|:.::.:.    ::.:.||     |:| :||.:||||:.......|:||.|..|.        .
Human     1 MWVPVVFLT----LSVTWIG-----AAP-LILSRIVGGWECEKHSQPWQVLVASRG--------R 47

  Fly    69 HVCGGAVISQRVVCSAAHCYAINTSVPLVYRDPELYVVVAGSSAIDRTDRFTQEYLVQRIVGHKD 133
            .||||.::..:.|.:||||.. |.|           |::.|..::...:...|.:.|.....|..
Human    48 AVCGGVLVHPQWVLTAAHCIR-NKS-----------VILLGRHSLFHPEDTGQVFQVSHSFPHPL 100

  Fly   134 YNGSTLEN-----------DIALLFLNGFIPWE-SPGVRAIPLAIKAPEEGTTCLIHGWGKVTMK 186
            |:.|.|:|           |:.||.|:.  |.| :..|:.:.|..:.|..||||...|||.:..:
Human   101 YDMSLLKNRFLRPGDDSSHDLMLLRLSE--PAELTDAVKVMDLPTQEPALGTTCYASGWGSIEPE 163

  Fly   187 E--KSASLQQAPVPILNKELCQVIY--KLPASQMCAGFLQGGIDACQGDSGGPLICDGRLAGIIS 247
            |  ....||...:.:::.::|..::  |:....:|||...||...|.|||||||:|:|.|.||.|
Human   164 EFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRWTGGKSTCSGDSGGPLVCNGVLQGITS 228

  Fly   248 WG-VGCADPGYPGVYTNVSHFLKWIR 272
            || ..||.|..|.:||.|.|:.|||:
Human   229 WGSEPCALPERPSLYTKVVHYRKWIK 254

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG32755	NP_727055.1	Tryp_SPc	38..273	CDD:238113	82/252 (33%)
KLK3	NP_001639.1	Tryp_SPc	25..256	CDD:238113	82/252 (33%)