DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32755 and OVCH1

DIOPT Version :9

Sequence 1:	NP_727055.1	Gene:	CG32755 / 318192	FlyBaseID:	FBgn0052755	Length:	315	Species:	Drosophila melanogaster
Sequence 2:	XP_024304736.1	Gene:	OVCH1 / 341350	HGNCID:	23080	Length:	1120	Species:	Homo sapiens

Alignment Length:	302	Identity:	96/302 - (31%)
Similarity:	141/302 - (46%)	Gaps:	43/302 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 VATHSGITQSQIGQPTATASPFVILPKIVGGYTVTIDQVPFQVSVRRRSIHERHYGLG-HVCGGA 74
            |:|...|.....|.|  ..||..:..:|.||........|:||.:|         .|| :.||||
Human   585 VSTVKAILHDVCGIP--PFSPQWLSRRIAGGEEACPHCWPWQVGLR---------FLGDYQCGGA 638

  Fly    75 VISQRVVCSAAHCYAINTSVPLVYRDPELYVVVAGSSAIDRTDRFTQEYLVQRIVGHKDYNGSTL 139
            :|:...:.:||||..:.       .:|..:.::||....:..:...|....:.|:.|:|:|..:.
Human   639 IINPVWILTAAHCVQLK-------NNPLSWTIIAGDHDRNLKESTEQVRRAKHIIVHEDFNTLSY 696

  Fly   140 ENDIALLFLNGFIPWESPGVRAIPLAIKAPE--EGTTCLIHGWGKVTMKEKSAS-LQQAPVPILN 201
            ::||||:.|:..:.:.|. ||.:.|...|..  ....|.:.|||.::.....|| |||..|.:|.
Human   697 DSDIALIQLSSPLEYNSV-VRPVCLPHSAEPLFSSEICAVTGWGSISADGGLASRLQQIQVHVLE 760

  Fly   202 KELCQVIY------KLPASQMCAGFLQGG-IDACQGDSGGPLICDGR-----LAGIISWGVGCAD 254
            :|:|:..|      .:....:||||...| .|.|||||||||:|...     |.||:|||.||..
Human   761 REVCEHTYYSAHPGGITEKMICAGFAASGEKDFCQGDSGGPLVCRHENGPFVLYGIVSWGAGCVQ 825

  Fly   255 PGYPGVYTNVSHFLKWIR---RANASLDYSE-----YRQIPP 288
            |..|||:..|..||.||:   ...|||..:.     .:|:||
Human   826 PWKPGVFARVMIFLDWIQSKINGPASLQTNNKCKTLKQQLPP 867

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32755	NP_727055.1	Tryp_SPc	37..271	CDD:214473	81/249 (33%)
CG32755	NP_727055.1	Tryp_SPc	38..273	CDD:238113	83/253 (33%)
OVCH1	XP_024304736.1	Tryp_SPc	58..294	CDD:238113
		CUB	336..444	CDD:238001
		CUB	454..565	CDD:238001
		Tryp_SPc	610..845	CDD:238113	83/251 (33%)
		CUB	881..978	CDD:238001
		CUB	1017..1119	CDD:238001
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910