DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32755 and tmprss4b

DIOPT Version :9

Sequence 1:	NP_727055.1	Gene:	CG32755 / 318192	FlyBaseID:	FBgn0052755	Length:	315	Species:	Drosophila melanogaster
Sequence 2:	NP_001119849.1	Gene:	tmprss4b / 327651	ZFINID:	ZDB-GENE-030131-5862	Length:	432	Species:	Danio rerio

Alignment Length:	253	Identity:	96/253 - (37%)
Similarity:	133/253 - (52%)	Gaps:	47/253 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 KIVGGYTVTIDQVPFQVSVRRRSIHERHYGLGHVCGGAVISQRVVCSAAHCYAINTSVPLVYRDP 101
            :||||...:|:..|:|||::        :...|:|||:::|...:.|||||:...|      ::.
Zfish   201 RIVGGVETSIEHWPWQVSLQ--------FNHRHMCGGSLLSTSWIISAAHCFTGRT------QEL 251

  Fly   102 ELYVVVAGSSAIDRTDRFTQEYLVQRIVGHKDYNGSTLENDIALLFLNGFIPWE-SPGVRAIP-- 163
            ..:.||.|.:.:......:    |..||.|||||..|.:.|||:|.|.    |. ..|...:|
Zfish   252 SRWTVVLGQTKVMDVVGVS----VDMIVIHKDYNRLTNDFDIAMLKLT----WPVKTGESILPVC 308

  Fly   164 -----LAIKAPEEGTTCLIHGWGKVTMKEKSA---SLQQAPVPILNKELCQ--VIY--KLPASQM 216
                 ||||     ...::.|||  .:||..|   .||:|.||::|:..|.  .||  .:....:
Zfish   309 LPPHQLAIK-----DMLVVTGWG--LLKEGGALPTVLQKASVPLVNRSECSKPTIYSSSITPRML 366

  Fly   217 CAGFLQGGIDACQGDSGGPLI---CDGRLAGIISWGVGCADPGYPGVYTNVSHFLKWI 271
            |||||||.:|||||||||||:   ...:|.||:|||||||..|.||||.:|:..|.||
Zfish   367 CAGFLQGNVDACQGDSGGPLVYLSSRWQLIGIVSWGVGCAREGKPGVYADVTQLLDWI 424

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32755	NP_727055.1	Tryp_SPc	37..271	CDD:214473	94/251 (37%)
CG32755	NP_727055.1	Tryp_SPc	38..273	CDD:238113	96/252 (38%)
tmprss4b	NP_001119849.1	SRCR_2	100..179	CDD:292133
		SRCR	105..>175	CDD:278931
		Tryp_SPc	201..424	CDD:214473	94/251 (37%)
		Tryp_SPc	202..427	CDD:238113	96/252 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24253
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	2.010