DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32755 and F12

DIOPT Version :9

Sequence 1:	NP_727055.1	Gene:	CG32755 / 318192	FlyBaseID:	FBgn0052755	Length:	315	Species:	Drosophila melanogaster
Sequence 2:	NP_001014028.1	Gene:	F12 / 306761	RGDID:	1359175	Length:	603	Species:	Rattus norvegicus

Alignment Length:	263	Identity:	88/263 - (33%)
Similarity:	125/263 - (47%)	Gaps:	40/263 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 LPKIVGGYTVTIDQVPFQVSVRRRSIHERHYGLGHVCGGAVISQRVVCSAAHCYAINTSVPLVYR 99
            |.::|||........|:..::         |.....|.|::|....|.:||||.....:
  Rat   359 LRRVVGGLVALPGSHPYIAAL---------YWGDSFCAGSLIDPCWVLTAAHCLQKRPA------ 408

  Fly   100 DPELYVVVAGSSAIDRTDRFTQEYLVQRIVGHKDYNGSTLENDIALLFLNG---FIPWESPGVR- 160
             ||...||.|....:::....|...|.....|:.::..|.::|:|||.|.|   .....||.|:
  Rat   409 -PEELTVVLGQDRHNQSCERCQTLAVHSYRLHEGFSSKTYQHDLALLRLRGRKNSCAILSPHVQP 472

  Fly   161 -AIPLAIKAPEEGTTCLIHGWGK--VTMKEKSASLQQAPVPILNKELC-------QVIYKLPASQ 215
             .:|.:...|.|...|.:.|||.  ...:|.:..||:|.||.::.:.|       ..|  || ..
  Rat   473 VCLPSSAAPPSETVLCEVAGWGHQFEGAEEYATFLQEAQVPFISLDRCSSSNVHGDAI--LP-GM 534

  Fly   216 MCAGFLQGGIDACQGDSGGPLICDG-------RLAGIISWGVGCADPGYPGVYTNVSHFLKWIRR 273
            :|||||:||.|||||||||||:||.       .|.|:||||.||.|...|||||:|:::|.||:.
  Rat   535 LCAGFLEGGADACQGDSGGPLVCDEGVTERQLTLRGVISWGSGCGDRNKPGVYTDVANYLDWIQE 599

  Fly   274 ANA 276
            ..|
  Rat   600 HTA 602

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32755	NP_727055.1	Tryp_SPc	37..271	CDD:214473	84/254 (33%)
CG32755	NP_727055.1	Tryp_SPc	38..273	CDD:238113	86/255 (34%)
F12	NP_001014028.1	FN2	40..87	CDD:238019
		EGF_CA	95..130	CDD:238011
		FN1	132..170	CDD:238018
		EGF	177..207	CDD:278437
		Kringle	216..294	CDD:278480
		Tryp_SPc	361..597	CDD:214473	84/254 (33%)
		Tryp_SPc	362..600	CDD:238113	86/256 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910