DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32755 and HABP2

DIOPT Version :9

Sequence 1:	NP_727055.1	Gene:	CG32755 / 318192	FlyBaseID:	FBgn0052755	Length:	315	Species:	Drosophila melanogaster
Sequence 2:	NP_004123.1	Gene:	HABP2 / 3026	HGNCID:	4798	Length:	560	Species:	Homo sapiens

Alignment Length:	252	Identity:	90/252 - (35%)
Similarity:	123/252 - (48%)	Gaps:	25/252 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 LPKIVGGYTVTIDQVPFQVSVRRRSIHERHYGLGHVCGGAVISQRVVCSAAHCYAINTSVPLVYR 99
            :.:|.||:..|..:.|:|.|::...........||.||||:|....|.:||||..|.|
Human   311 IKRIYGGFKSTAGKHPWQASLQSSLPLTISMPQGHFCGGALIHPCWVLTAAHCTDIKT------- 368

  Fly   100 DPELYVVVAGSSAIDRTDRFTQEYLVQRIVGHKDYN--GSTLENDIALLFL---NGFIPWESPGV 159
              ....||.|...:.:.:...|.:.|::|..:..||  .....||||||.|   :|....||..|
Human   369 --RHLKVVLGDQDLKKEEFHEQSFRVEKIFKYSHYNERDEIPHNDIALLKLKPVDGHCALESKYV 431

  Fly   160 RAIPLAIKAPEEGTTCLIHGWGKVTMKEKSASLQQAPVPILNKELC--QVIY--KLPASQMCAGF 220
            :.:.|...:...|:.|.|.|||.....:.|..|..|.|.::...||  :.:|  .:..|.:|||.
Human   432 KTVCLPDGSFPSGSECHISGWGVTETGKGSRQLLDAKVKLIANTLCNSRQLYDHMIDDSMICAGN 496

  Fly   221 LQ-GGIDACQGDSGGPLIC--DGR--LAGIISWGVGCADPGYPGVYTNVSHFLKWIR 272
            || .|.|.|||||||||.|  ||.  :.||:|||:.|..  .|||||.|:.||.||:
Human   497 LQKPGQDTCQGDSGGPLTCEKDGTYYVYGIVSWGLECGK--RPGVYTQVTKFLNWIK 551

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32755	NP_727055.1	Tryp_SPc	37..271	CDD:214473	88/247 (36%)
CG32755	NP_727055.1	Tryp_SPc	38..273	CDD:238113	90/249 (36%)
HABP2	NP_004123.1	EGF	77..106	CDD:306513
		KR	191..277	CDD:238056
		Tryp_SPc	314..553	CDD:238113	90/249 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910