Protein Alignment CG32755 and GZMH

DIOPT Version :9

• Sequence 1: NP_727055.1
• Gene: CG32755 / 318192
• FlyBaseID: FBgn0052755
• Length: 315
• Species: Drosophila melanogaster
• Sequence 2: NP_219491.1
• Gene: GZMH / 2999
• HGNCID: 4710
• Length: 246
• Species: Homo sapiens
• Alignment Length: 268
• Identity: 81/268 - (30%)
• Similarity: 124/268 - (46%)
• Gaps: 46/268 - (17%)

  Fly    24 QPTATASPFVILP-----KIVGGYTVTIDQVPFQVSV-------RRRSIHERHYGLGHVCGGAVI 76
            ||......|::.|     :|:||:.......|:...|       |:|            |||.::
Human     2 QPFLLLLAFLLTPGAGTEEIIGGHEAKPHSRPYMAFVQFLQEKSRKR------------CGGILV 54

  Fly    77 SQRVVCSAAHCYAINTSVPLVYRDPELYVVVAGSSAIDRTDRFTQEYL-VQRIVGHKDYNGSTLE 140
            .:..|.:||||...:.:|.|            |:..|...:| ||::: |:|.:.|..||.....
Human    55 RKDFVLTAAHCQGSSINVTL------------GAHNIKEQER-TQQFIPVKRPIPHPAYNPKNFS 106

  Fly   141 NDIALLFLNGFIPWESPGVRAIPL-AIKAP-EEGTTCLIHGWGKVTMKEKSASLQQAPVPILNKE 203
            |||.||.|.....| :..||.:.| :.||. :.|..|.:.|||.|:|...:.:||:..:.:....
Human   107 NDIMLLQLERKAKW-TTAVRPLRLPSSKAQVKPGQLCSVAGWGYVSMSTLATTLQEVLLTVQKDC 170

  Fly   204 LCQVIYK---LPASQMCAGFLQGGIDACQGDSGGPLICDGRLAGIISWGVGCADPGYPGVYTNVS 265
            .|:.::.   ..|:::|.|..:......:|||||||:|.....||:|:|.....|  ||||..||
Human   171 QCERLFHGNYSRATEICVGDPKKTQTGFKGDSGGPLVCKDVAQGILSYGNKKGTP--PGVYIKVS 233

  Fly   266 HFLKWIRR 273
            |||.||:|
Human   234 HFLPWIKR 241

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG32755	NP_727055.1	Tryp_SPc	37..271	CDD:214473	74/246 (30%)
		Tryp_SPc	38..273	CDD:238113	76/247 (31%)
GZMH	NP_219491.1	Tryp_SPc	21..242	CDD:238113	77/249 (31%)
		Mediates the preference for acidic residues at the P3' and P4' sites	46..48		1/1 (100%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910