DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG32755 and Tmprss5

DIOPT Version :9

Sequence 1:	NP_727055.1	Gene:	CG32755 / 318192	FlyBaseID:	FBgn0052755	Length:	315	Species:	Drosophila melanogaster
Sequence 2:	NP_695223.2	Gene:	Tmprss5 / 266681	RGDID:	628625	Length:	445	Species:	Rattus norvegicus

Alignment Length:	248	Identity:	91/248 - (36%)
Similarity:	129/248 - (52%)	Gaps:	29/248 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 KIVGGYTVTIDQVPFQVSVRRRSIHERHYGLGHVCGGAVISQRVVCSAAHC-YAINTSVPLVYRD 100
            :||||..|...:.|:|.||.        .|..|.||.:|::...|.:|||| |:...|....:|
  Rat   207 RIVGGQAVASGRWPWQASVM--------LGSRHTCGASVLAPYWVVTAAHCMYSFRLSRLSSWR- 262

  Fly   101 PELYVVVAGSSAIDRTDRFTQEYLVQRIVGHKDYNGSTLENDIALLFLNGFIPWESPGVRAIPLA 165
              ::..:...||:    |..|..:|::|:.|..|:....:.|:|||.|...|.: |..|.|:.|.
  Rat   263 --VHAGLVSHSAV----RQHQGTMVEKIIPHPLYSAQNHDYDVALLQLRTPINF-SDTVSAVCLP 320

  Fly   166 IKAPE--EGTTCLIHGWGKV--TMKEKSASLQQAPVPILNKELC--QVIYK--LPASQMCAGFLQ 222
            .|...  :|:.|.:.|||..  :....|.:||...||:|:.:||  ..:|.  |....:|||:|.
  Rat   321 AKEQHFPQGSQCWVSGWGHTDPSHTHSSDTLQDTMVPLLSTDLCNSSCMYSGALTHRMLCAGYLD 385

  Fly   223 GGIDACQGDSGGPLICDG----RLAGIISWGVGCADPGYPGVYTNVSHFLKWI 271
            |..|||||||||||:|..    .|.|::|||.|||:|..||||..|:.||.||
  Rat   386 GRADACQGDSGGPLVCPSGDTWHLVGVVSWGRGCAEPNRPGVYAKVAEFLDWI 438

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32755	NP_727055.1	Tryp_SPc	37..271	CDD:214473	89/246 (36%)
CG32755	NP_727055.1	Tryp_SPc	38..273	CDD:238113	91/247 (37%)
Tmprss5	NP_695223.2	SRCR_2	106..203	CDD:406055
Tmprss5	NP_695223.2	Tryp_SPc	208..441	CDD:238113	91/247 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR24253
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010