DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG32755 and Tmprss11f

DIOPT Version :9

Sequence 1:	NP_727055.1	Gene:	CG32755 / 318192	FlyBaseID:	FBgn0052755	Length:	315	Species:	Drosophila melanogaster
Sequence 2:	NP_848845.1	Gene:	Tmprss11f / 243083	MGIID:	2442348	Length:	439	Species:	Mus musculus

Alignment Length:	278	Identity:	90/278 - (32%)
Similarity:	142/278 - (51%)	Gaps:	42/278 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 IVATHSGITQSQIGQPTATASPFVILPKIVGGYTVTID-QVPFQVSVRRRSIHERHYGLGHVCGG 73
            ::.:..||..|....|...:|.   ..:||.|....:: :.|:|.|::.       .|.||.||.
Mouse   182 LLNSRCGIRMSSSNIPLPASSS---TERIVQGRETAMEGEWPWQASLQL-------IGAGHQCGA 236

  Fly    74 AVISQRVVCSAAHCYAINTSVPLVYRDPELYVVVAGSSAIDRTDRFTQEYLVQRIVG----HKDY 134
            .:||...:.:||||:..|       |||..::|..|::....        ||:|.||    |::|
Mouse   237 TLISNTWLLTAAHCFWKN-------RDPTKWIVTFGTTITPP--------LVKRSVGKIIIHEEY 286

  Fly   135 NGSTLENDIALLFLNGFIPWESPGVR-AIP-LAIKAPEEGTTCLIHGWGKVTMKEKSAS-LQQAP 196
            :..|.||||||..|...:.:.:...| .:| .::|.|.: |:..:.|:|.:.....:.: |:||.
Mouse   287 HRDTNENDIALAQLTTRVEFSNVVQRVCLPDSSMKLPPK-TSVFVTGFGSIVDDGPTQNKLRQAR 350

  Fly   197 VPILNKELC--QVIYK--LPASQMCAGFLQGGIDACQGDSGGPLICDGR----LAGIISWGVGCA 253
            |..:..::|  :.:|.  :....:||||::|.||||:|||||||:.|.|    :.||:|||..||
Mouse   351 VETIGSDVCNRKDVYDGLITPGMLCAGFMEGKIDACKGDSGGPLVYDNRDIWYIVGIVSWGQSCA 415

  Fly   254 DPGYPGVYTNVSHFLKWI 271
            .|..|||||.|:.:..||
Mouse   416 LPNKPGVYTRVTKYRDWI 433

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32755	NP_727055.1	Tryp_SPc	37..271	CDD:214473	83/249 (33%)
CG32755	NP_727055.1	Tryp_SPc	38..273	CDD:238113	85/250 (34%)
Tmprss11f	NP_848845.1	SEA	60..164	CDD:396113
Tmprss11f	NP_848845.1	Tryp_SPc	207..436	CDD:238113	85/250 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910