Protein Alignment CG32755 and F12

DIOPT Version :10

• Sequence 1: NP_727055.1
• Gene: CG32755 / 318192
• FlyBaseID: FBgn0052755
• Length: 315
• Species: Drosophila melanogaster
• Sequence 2: NP_000496.2
• Gene: F12 / 2161
• HGNCID: 3530
• Length: 615
• Species: Homo sapiens
• Alignment Length: 266
• Identity: 93/266 - (34%)
• Similarity: 131/266 - (49%)
• Gaps: 43/266 - (16%)

  Fly    35 LPKIVGGYTVTIDQVPFQVSVRRRSIHERHYGL--GH-VCGGAVISQRVVCSAAHCYAINTSVPL 96
            :.::|||.            |..|..|.....|  || .|.|::|:...|.:||||.....:
Human   370 MTRVVGGL------------VALRGAHPYIAALYWGHSFCAGSLIAPCWVLTAAHCLQDRPA--- 419

  Fly    97 VYRDPELYVVVAGSSAIDRTDRFTQEYLVQRIVGHKDYNGSTLENDIALLFL----NGFIPWESP 157
                ||...||.|....:.:....|...|:....|:.::..:.::|:|||.|    :|.....||
Human   420 ----PEDLTVVLGQERRNHSCEPCQTLAVRSYRLHEAFSPVSYQHDLALLRLQEDADGSCALLSP 480

  Fly   158 GVR--AIPLAIKAPEEGTTCLIHGWGK--VTMKEKSASLQQAPVPILNKELCQV--IYK---LPA 213
            .|:  .:|.....|.|.|.|.:.|||.  ...:|.::.||:|.||.|:.|.|..  ::.   ||
Human   481 YVQPVCLPSGAARPSETTLCQVAGWGHQFEGAEEYASFLQEAQVPFLSLERCSAPDVHGSSILP- 544

  Fly   214 SQMCAGFLQGGIDACQGDSGGPLICDGR-------LAGIISWGVGCADPGYPGVYTNVSHFLKWI 271
            ..:|||||:||.|||||||||||:|:.:       |.||||||.||.|...|||||:|:::|.||
Human   545 GMLCAGFLEGGTDACQGDSGGPLVCEDQAAERRLTLQGIISWGSGCGDRNKPGVYTDVAYYLAWI 609

  Fly   272 RRANAS 277
            |....|
Human   610 REHTVS 615

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG32755	NP_727055.1	Tryp_SPc	38..273	CDD:238113	91/257 (35%)
F12	NP_000496.2	FN2	41..88	CDD:128373
		EGF_CA	96..131	CDD:238011
		FN1	133..173	CDD:238018
		EGF	178..206	CDD:394967
		Kringle	217..295	CDD:395005
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	298..359
		Tryp_SPc	373..612	CDD:238113	92/258 (36%)