DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG32755 and F11

DIOPT Version :9

Sequence 1:	NP_727055.1	Gene:	CG32755 / 318192	FlyBaseID:	FBgn0052755	Length:	315	Species:	Drosophila melanogaster
Sequence 2:	XP_005262878.1	Gene:	F11 / 2160	HGNCID:	3529	Length:	626	Species:	Homo sapiens

Alignment Length:	253	Identity:	92/253 - (36%)
Similarity:	132/253 - (52%)	Gaps:	33/253 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 ILPKIVGGYTVTIDQVPFQVSVRRRSIHERHYGLGHVCGGAVISQRVVCSAAHC-YAINTSVPLV 97
            |.|:||||......:.|:||::...|..:|     |:|||::|..:.:.:|||| |.:.:  |.:
Human   385 IKPRIVGGTASVRGEWPWQVTLHTTSPTQR-----HLCGGSIIGNQWILTAAHCFYGVES--PKI 442

  Fly    98 YRDPELYVVVAGSSAIDRTDRFTQEYLVQRIVGHKDYNGSTLENDIALLFLNGFIPWESPGVRAI 162
            .|   :|..:...|.|.....|   :.||.|:.|..|..:....|||||.|...:.: :...|.|
Human   443 LR---VYSGILNQSEIKEDTSF---FGVQEIIIHDQYKMAESGYDIALLKLETTVNY-TDSQRPI 500

  Fly   163 PLAIKAPEEG------TTCLIHGWGKVTMKEK-SASLQQAPVPILNKELCQVIY---KLPASQMC 217
            .|    |.:|      |.|.:.|||...:::| ..:||:|.:|::..|.||..|   |:....:|
Human   501 CL----PSKGDRNVIYTDCWVTGWGYRKLRDKIQNTLQKAKIPLVTNEECQKRYRGHKITHKMIC 561

  Fly   218 AGFLQGGIDACQGDSGGPLICD----GRLAGIISWGVGCADPGYPGVYTNVSHFLKWI 271
            ||:.:||.|||:|||||||.|.    ..|.||.|||.|||....|||||||..::.||
Human   562 AGYREGGKDACKGDSGGPLSCKHNEVWHLVGITSWGEGCAQRERPGVYTNVVEYVDWI 619

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32755	NP_727055.1	Tryp_SPc	37..271	CDD:214473	88/248 (35%)
CG32755	NP_727055.1	Tryp_SPc	38..273	CDD:238113	90/249 (36%)
F11	XP_005262878.1	APPLE	20..103	CDD:128519
		APPLE	110..193	CDD:128519
		APPLE	200..283	CDD:128519
		APPLE	291..375	CDD:128519
		Tryp_SPc	388..619	CDD:214473	88/248 (35%)
		Tryp_SPc	389..619	CDD:238113	88/247 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910