DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32755 and svh-1

DIOPT Version :9

Sequence 1:	NP_727055.1	Gene:	CG32755 / 318192	FlyBaseID:	FBgn0052755	Length:	315	Species:	Drosophila melanogaster
Sequence 2:	NP_501379.2	Gene:	svh-1 / 182375	WormBaseID:	WBGene00006620	Length:	951	Species:	Caenorhabditis elegans

Alignment Length:	277	Identity:	89/277 - (32%)
Similarity:	141/277 - (50%)	Gaps:	41/277 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 ATHSGITQSQIGQPTATASPFVILPKIVGGYTVTIDQVPFQVSVRRRSIHERHYGLGHVCGGAVI 76
            |:..|:...::....|..|.   :.::|||:.......|:..::|.::....|      ||.:::
Worm   690 ASQCGLRYVEVNARDAAKSR---IARVVGGFETVPGAFPWTAALRNKATKAHH------CGASIL 745

  Fly    77 SQRVVCSAAHCYAINTSVPLVYRDPELYVVVAGSSAIDRTDRFTQEYLVQRIVGHKDYNGSTLEN 141
            .:..:.:||||:..:..|       ..|.||.|....::||...|.:.:|||..:..|. ....:
Worm   746 DKTHLITAAHCFEEDERV-------SSYEVVVGDWDNNQTDGNEQIFYLQRIHFYPLYK-DIFSH 802

  Fly   142 DIALLFLNGFIPWESPGVR----AIPLAIKAPE----EGTTCLIHGWGKVTMKEKSASLQQAPVP 198
            |||:|    .||:  ||:.    |.|:.:.:.:    .|..|::.|||.:.:: .:..||.|.:|
Worm   803 DIAIL----EIPY--PGIEFNEYAQPICLPSKDFVYTPGRQCVVSGWGSMGLR-YAERLQAALIP 860

  Fly   199 ILNKELC----QVIYKLPASQMCAGFLQGGIDACQGDSGGPLIC---DGR--LAGIISWGVGCAD 254
            |:|:..|    |:...:..|..|||:|:||||:||||||||..|   ||.  |||:||||.|||.
Worm   861 IINRFDCVNSSQIYSSMSRSAFCAGYLEGGIDSCQGDSGGPFACRREDGAFVLAGVISWGDGCAQ 925

  Fly   255 PGYPGVYTNVSHFLKWI 271
            ...||:||.|:.:|.||
Worm   926 KKQPGIYTMVAPYLSWI 942

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32755	NP_727055.1	Tryp_SPc	37..271	CDD:214473	83/250 (33%)
CG32755	NP_727055.1	Tryp_SPc	38..273	CDD:238113	85/251 (34%)
svh-1	NP_501379.2	KR	227..306	CDD:214527
		LDLa	320..355	CDD:238060
		PAN_AP_HGF	373..434	CDD:238532
		LDLa	558..590	CDD:197566
		SRCR_2	599..681	CDD:382996
		Tryp_SPc	713..945	CDD:238113	85/251 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910