DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32755 and PRSS36

DIOPT Version :9

Sequence 1:	NP_727055.1	Gene:	CG32755 / 318192	FlyBaseID:	FBgn0052755	Length:	315	Species:	Drosophila melanogaster
Sequence 2:	NP_775773.2	Gene:	PRSS36 / 146547	HGNCID:	26906	Length:	855	Species:	Homo sapiens

Alignment Length:	273	Identity:	90/273 - (32%)
Similarity:	126/273 - (46%)	Gaps:	47/273 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 GQPTATASPFVILPKIVGGYTVTIDQVPFQVSVRRRSIHERHYGLGHVCGGAVISQRVVCSAAHC 87
            |:|..:|       :||||........|:|||:        |:|.||:|||::|:...|.|||||
Human    39 GRPEPSA-------RIVGGSNAQPGTWPWQVSL--------HHGGGHICGGSLIAPSWVLSAAHC 88

  Fly    88 YAINTSVPLVYRDPEL-YVVVAGSSAIDRTDRFTQEYLVQRIVGHKDYNGSTLENDIALLFLN-- 149
            :..|.::     :|.. :.|:.|..:.|..........|..||...:|:...|..|:|||.|.
Human    89 FMTNGTL-----EPAAEWSVLLGVHSQDGPLDGAHTRAVAAIVVPANYSQVELGADLALLRLASP 148

  Fly   150 ---GFIPWESPGVRAIPLAIKAPEEGTTCLIHGWGKVTMKEKSA---SLQQAPVPILNKELCQVI 208
               |...|..    .:|.|......||.|...|||.|...:...   .||:..:.:|.:..||.:
Human   149 ASLGPAVWPV----CLPRASHRFVHGTACWATGWGDVQEADPLPLPWVLQEVELRLLGEATCQCL 209

  Fly   209 YKLPA----------SQMCAGFLQGGIDACQGDSGGPLICD--GR--LAGIISWGVGCADPGYPG 259
            |..|.          ..:|||:.:|..|.|||||||||:|:  ||  .|||.|:|.||.....||
Human   210 YSQPGPFNLTLQILPGMLCAGYPEGRRDTCQGDSGGPLVCEEGGRWFQAGITSFGFGCGRRNRPG 274

  Fly   260 VYTNVSHFLKWIR 272
            |:|.|:.:..|||
Human   275 VFTAVATYEAWIR 287

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32755	NP_727055.1	Tryp_SPc	37..271	CDD:214473	84/256 (33%)
CG32755	NP_727055.1	Tryp_SPc	38..273	CDD:238113	87/258 (34%)
PRSS36	NP_775773.2	Tryp_SPc	46..286	CDD:214473	84/256 (33%)
		Tryp_SPc	47..289	CDD:238113	87/258 (34%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	292..316
		Tryp_SPc	330..538	CDD:304450
		Tryp_SPc	601..783	CDD:304450
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910