DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32755 and Tmprss3

DIOPT Version :9

Sequence 1:	NP_727055.1	Gene:	CG32755 / 318192	FlyBaseID:	FBgn0052755	Length:	315	Species:	Drosophila melanogaster
Sequence 2:	NP_001157248.1	Gene:	Tmprss3 / 140765	MGIID:	2155445	Length:	475	Species:	Mus musculus

Alignment Length:	252	Identity:	89/252 - (35%)
Similarity:	135/252 - (53%)	Gaps:	39/252 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 PKIVGGYTVTIDQVPFQVSVRRRSIHERHYGLGHVCGGAVISQRVVCSAAHCYAINTSVPLVY-- 98
            |:||||...::.|.|:|||::.:..        |:|||::|:...:.:||||         ||
Mouse   237 PRIVGGNMSSLTQWPWQVSLQFQGY--------HLCGGSIITPLWIVTAAHC---------VYDL 284

  Fly    99 RDPELYVVVAGSSAIDRTDRFTQEYLVQRIVGHKDYNGSTLENDIALLFLNGFIPWESPGVRAIP 163
            ..|:.:.|..|  .:...|.....:||::|:.|..|....|.|||||:.|:..:.::.   ...|
Mouse   285 YHPKSWTVQVG--LVSLMDSPVPSHLVEKIIYHSKYKPKRLGNDIALMKLSEPLTFDE---TIQP 344

  Fly   164 LAIKAPEE----GTTCLIHGWGKVTMKEKSAS--LQQAPVPILNKELC--QVIYK--LPASQMCA 218
            :.:...||    |..|...||| .|.....||  |..|.||:::.::|  :.:|.  :..|.:||
Mouse   345 ICLPNSEENFPDGKLCWTSGWG-ATEDGGDASPVLNHAAVPLISNKICNHRDVYGGIISPSMLCA 408

  Fly   219 GFLQGGIDACQGDSGGPLICDGR----LAGIISWGVGCADPGYPGVYTNVSHFLKWI 271
            |:|:||:|:|||||||||:|..|    |.|..|:|:|||:...|||||.::.||.||
Mouse   409 GYLKGGVDSCQGDSGGPLVCQERRLWKLVGATSFGIGCAEVNKPGVYTRITSFLDWI 465

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32755	NP_727055.1	Tryp_SPc	37..271	CDD:214473	86/249 (35%)
CG32755	NP_727055.1	Tryp_SPc	38..273	CDD:238113	88/250 (35%)
Tmprss3	NP_001157248.1	LDLa	96..129	CDD:238060
		SRCR_2	134..233	CDD:292133
		Tryp_SPc	238..465	CDD:214473	86/249 (35%)
		Tryp_SPc	239..468	CDD:238113	88/250 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910