DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32755 and AgaP_AGAP001365

DIOPT Version :9

Sequence 1:	NP_727055.1	Gene:	CG32755 / 318192	FlyBaseID:	FBgn0052755	Length:	315	Species:	Drosophila melanogaster
Sequence 2:	XP_321778.5	Gene:	AgaP_AGAP001365 / 1281817	VectorBaseID:	AGAP001365	Length:	608	Species:	Anopheles gambiae

Alignment Length:	275	Identity:	81/275 - (29%)
Similarity:	120/275 - (43%)	Gaps:	48/275 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 QPTATASPFVILPKIVGGYTVTIDQVPFQVSVRRRSIHERHYGLGHVCGGAVISQRVVCSAAHCY 88
            :|..|.    |..:|:||.|....:.|:.|::   .:.|.:.     |||::|.:|.:.:||||.
Mosquito   354 EPVGTR----IRSRIIGGVTSNQGEHPWHVAI---YLDEEYQ-----CGGSIIGRRWILTAAHCL 406

  Fly    89 A-INTSVPLVYRDPELYVVVAG---SSAIDRTDRFTQEYLVQRIVGHKDYNGSTLENDIALLFL- 148
            . .||:..|   |.:|:.|..|   .|.||  |.|.:  ....::.|:|||......||.||.|
Mosquito   407 TRQNTNETL---DVDLFRVYTGIIDISTID--DHFYR--TADEVIVHRDYNPVMYTTDIGLLRLK 464

  Fly   149 -----NGFIPWESPGVRAIPLAIKAPEEGTTCLIHGWGKVTMKEKSASLQQAPVPILNKELC--- 205
                 |.||.......|.:.::.....||.   :.|||.......|..|....||::::::|
Mosquito   465 RNITYNSFIKPVCLYNRTVDISTFYGREGK---VTGWGFNRDGVISNVLNYLEVPVVSQKMCSQR 526

  Fly   206 QVIYK---LPASQMCAGFLQGGIDACQGDSGGPLI-CDG---RLAGIISWGVG-----CADPGYP 258
            .|.:.   ......|||...|. ..|.|||||.|: .:|   .:.||:|....     ..||...
Mosquito   527 NVQFNGVLAVGESFCAGHADGN-SVCNGDSGGGLVFAEGPRYYVRGIVSISAQRRNLLLCDPNQY 590

  Fly   259 GVYTNVSHFLKWIRR 273
            .|:|:||.||.|||:
Mosquito   591 SVFTDVSKFLNWIRQ 605

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32755	NP_727055.1	Tryp_SPc	37..271	CDD:214473	75/258 (29%)
CG32755	NP_727055.1	Tryp_SPc	38..273	CDD:238113	77/259 (30%)
AgaP_AGAP001365	XP_321778.5	GD_N	42..144	CDD:292649
		GD_N	190..297	CDD:292649
		Tryp_SPc	363..603	CDD:214473	75/258 (29%)
		Tryp_SPc	364..606	CDD:238113	78/261 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910