DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32755 and prss12

DIOPT Version :9

Sequence 1:	NP_727055.1	Gene:	CG32755 / 318192	FlyBaseID:	FBgn0052755	Length:	315	Species:	Drosophila melanogaster
Sequence 2:	XP_002934300.3	Gene:	prss12 / 100495119	XenbaseID:	XB-GENE-984837	Length:	851	Species:	Xenopus tropicalis

Alignment Length:	261	Identity:	88/261 - (33%)
Similarity:	130/261 - (49%)	Gaps:	45/261 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 KIVGGYTVTIDQVPFQVSVRRRSIHERHYGLGH-VCGGAVISQRVVCSAAHC---YAINTSVPLV 97
            :|:||........|:||::|.:|.|    |.|. :||..:||...|.:||||   |..||
Frog   606 RIIGGKNSVRGGWPWQVALRLKSSH----GDGRLLCGATLISSCWVLTAAHCFKRYGNNT----- 661

  Fly    98 YRDPELYVVVAGSSAIDRTDRFTQEYLVQRIVGHKDYNGSTLENDIALLFLNG-----------F 151
                ..||:..|.......:.:.::..:|:|:.|.||.....:.||||:.|:|           .
Frog   662 ----RSYVIRVGDYHTLVPEEYEEDMTIQQIIIHNDYRPDGNDYDIALIRLHGTAEQCVQLSTHV 722

  Fly   152 IPWESPGVRAIPLAIKAPEE-GTTCLIHGWGKVTMKEKSASLQQAPVPILNKELCQVIYK--LPA 213
            :|      ..:||..:.|:: .:.|.|.|||. |.:..|.:||||.|.:|.|.:|:..|:  ...
Frog   723 LP------ACLPLRRERPQKTASNCYITGWGD-TGRAYSRTLQQATVTLLPKRVCEERYRSQFTG 780

  Fly   214 SQMCAGFL--QGGIDACQGDSGGPLICDGR-----LAGIISWGVGCADPGYPGVYTNVSHFLKWI 271
            ..:|||.:  |..:|:|||||||||:|:..     :.|:.|||.||.....|||||.||.|:.||
Frog   781 RMLCAGSVKTQKHVDSCQGDSGGPLVCERSGGSWIVYGVTSWGYGCGVKDSPGVYTKVSAFIPWI 845

  Fly   272 R 272
            :
Frog   846 K 846

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32755	NP_727055.1	Tryp_SPc	37..271	CDD:214473	86/258 (33%)
CG32755	NP_727055.1	Tryp_SPc	38..273	CDD:238113	88/260 (34%)
prss12	XP_002934300.3	KR	78..140	CDD:412161
		SRCR	148..244	CDD:395421
		SR	257..356	CDD:214555
		SR	363..461	CDD:214555
		SR	476..575	CDD:214555
		Tryp_SPc	607..848	CDD:238113	88/260 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910