DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32755 and corin

DIOPT Version :9

Sequence 1:	NP_727055.1	Gene:	CG32755 / 318192	FlyBaseID:	FBgn0052755	Length:	315	Species:	Drosophila melanogaster
Sequence 2:	XP_004911266.2	Gene:	corin / 100492163	XenbaseID:	XB-GENE-950958	Length:	1123	Species:	Xenopus tropicalis

Alignment Length:	268	Identity:	93/268 - (34%)
Similarity:	139/268 - (51%)	Gaps:	33/268 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 TQSQIG-QPTATASPFVILPKIVGGYTVTIDQVPFQVSVRRRSIHERHYGLGHVCGGAVISQRVV 81
            |:...| :|.|..|     .:|:||.|....:.|:|.|::...       .||:||..:|.::.|
Frog   867 TKEDCGRRPAARMS-----KRILGGRTSRPGRWPWQCSLQSDP-------SGHICGCVLIGKKWV 919

  Fly    82 CSAAHCYAINTSVPLVYRDPELYVVVAGSSAIDRTDRFTQEYLVQRIVGHKDYNGSTLENDIALL 146
            .:.|||:....|.       .::.||.|.:.:|....|.|..||::|:.|..||.:.::.||:::
Frog   920 LTVAHCFEGRESA-------AVWKVVFGINNLDHPSDFAQTRLVKKIILHPRYNRAVVDYDISIV 977

  Fly   147 FLNGFIPWESPGVRAIPLAIKAP--EEGTTCLIHGWGKVTMKEKSASLQQAPVPILNKELCQVIY 209
            .||..|. |:..||.:.|..|..  |..|.|.|.|||.:..| ....||:..|.|::.|.||..:
Frog   978 ELNEDIT-ETSYVRPVCLPTKGQLVEPDTYCYITGWGHMGNK-MPFKLQEGEVRIISLERCQSYF 1040

  Fly   210 ---KLPASQMCAGFLQGGIDACQGDSGGPLICD---GR--LAGIISWGVGCADPGY-PGVYTNVS 265
               .:.:..:|||:..|.||:|.|||||||:|:   |:  |.|:.|||..|..... ||||:|||
Frog  1041 DMKTITSRMLCAGYESGTIDSCMGDSGGPLVCEKPGGKWTLYGLTSWGSVCFSKVLGPGVYSNVS 1105

  Fly   266 HFLKWIRR 273
            ||::||.|
Frog  1106 HFVEWIER 1113

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32755	NP_727055.1	Tryp_SPc	37..271	CDD:214473	85/244 (35%)
CG32755	NP_727055.1	Tryp_SPc	38..273	CDD:238113	87/245 (36%)
corin	XP_004911266.2	CRD_corin_1	213..341	CDD:143554
		LDLa	351..382	CDD:238060
		LDLa	384..418	CDD:238060
		LDLa	420..455	CDD:238060
		LDLa	465..492	CDD:238060
		CRD_corin_2	533..654	CDD:143579
		LDLa	659..693	CDD:238060
		LDLa	734..768	CDD:238060
		Tryp_SPc	883..1114	CDD:238113	88/247 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910