DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32755 and proc.2

DIOPT Version :9

Sequence 1:	NP_727055.1	Gene:	CG32755 / 318192	FlyBaseID:	FBgn0052755	Length:	315	Species:	Drosophila melanogaster
Sequence 2:	NP_001120289.1	Gene:	proc.2 / 100145345	XenbaseID:	XB-GENE-5882297	Length:	681	Species:	Xenopus tropicalis

Alignment Length:	317	Identity:	98/317 - (30%)
Similarity:	148/317 - (46%)	Gaps:	69/317 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MDHLWMCLLIVATHSGITQSQIGQPTATASPFVILP----------KIVGGYTVTIDQVPFQVSV 55
            :||..:...:.|..:|.::|...:....||   :.|          :||||....:.|.|:||.:
Frog   392 LDHNEIGASVRAARTGTSKSVWEENHGLAS---VEPDDYNTPDGDVRIVGGMRCELGQCPWQVLI 453

  Fly    56 RRRSIHERHYGLGHVCGGAVISQRVVCSAAHCYAINTSVPLVYRDPELYVVVAGSSAIDRTDRFT 120
            |    :.|.:|.   |||::||.|.|.|||||:  .:.:|        :.|..|.....|.|...
Frog   454 R----NNRGFGF---CGGSLISSRWVLSAAHCF--ESQIP--------HHVTIGDYDTYRRDMDE 501

  Fly   121 QEYLVQRIVGHKDYNGSTLENDIALLFLNGFIPWESP---GVRAIPLAIKAP-------EEGTTC 175
            |:..|.::..|.:|.....::|||||||      .||   |..:.|:.:..|       :||.|.
Frog   502 QKIAVLQVFSHPNYLAEFYDHDIALLFL------RSPAMFGEYSRPICLPNPGLGKMLTQEGQTG 560

  Fly   176 LIHGWGKVTMKEKSASLQQAP---------VPILNKELCQVIYK--LPASQMCAGFLQGGIDACQ 229
            .:.|||        |:.|..|         :||:::|.|....:  |..:..|||:.:|..|||.
Frog   561 QVSGWG--------ATRQFGPYTRFLLKVRLPIVSQETCMASTENILTGNMFCAGYKEGVKDACS 617

  Fly   230 GDSGGP---LICD-GRLAGIISWGVGCADPGYPGVYTNVSHFLKWIRRANASLDYSE 282
            ||||||   |..| ..|.|::|||.|||:.|..||||.|::::.||:.....::..|
Frog   618 GDSGGPFAVLFHDTWFLVGVVSWGDGCAEKGKYGVYTRVANYMPWIKETIVEIEEGE 674

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32755	NP_727055.1	Tryp_SPc	37..271	CDD:214473	87/258 (34%)
CG32755	NP_727055.1	Tryp_SPc	38..273	CDD:238113	89/259 (34%)
proc.2	NP_001120289.1	GLA	19..80	CDD:214503
		EGF_CA	81..117	CDD:238011
		FXa_inhibition	123..160	CDD:373209
		Tryp_SPc	436..666	CDD:238113	89/260 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910