DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32755 and tmprss3a

DIOPT Version :9

Sequence 1:	NP_727055.1	Gene:	CG32755 / 318192	FlyBaseID:	FBgn0052755	Length:	315	Species:	Drosophila melanogaster
Sequence 2:	XP_021334565.1	Gene:	tmprss3a / 100000148	ZFINID:	ZDB-GENE-070912-70	Length:	543	Species:	Danio rerio

Alignment Length:	307	Identity:	102/307 - (33%)
Similarity:	150/307 - (48%)	Gaps:	59/307 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 THSGITQSQIGQPT-----ATASPFVILPKIVGGYTVTIDQVPFQVSVRRRSIHERHYGLGHVCG 72
            |:|..|:..:|..|     |..|......:||||......|.|:|||:        |:...|:||
Zfish   268 TNSSKTKCSLGMVTALKCIACGSRPKFSARIVGGNLSAEGQFPWQVSL--------HFQNEHLCG 324

  Fly    73 GAVISQRVVCSAAHC-YAINTSVPLVYRDPELYVVVAGSSAIDRTDRFTQEYLVQRIVGHKDYNG 136
            |::|:.|.:.:|||| |.|      .|  |..::|.||.:.:..  ...:.:.|::|:.|..|..
Zfish   325 GSIITSRWILTAAHCVYGI------AY--PMYWMVYAGLTELPL--NAVKAFAVEKIIYHSRYRP 379

  Fly   137 STLENDIALLFL------NGFIPWESPGVRAIPLAI----KAPEEGTTCLIHGWGKVTMKEKSAS 191
            ..|::||||:.|      ||.:.         |:.:    :..|:|..|.|.||| .|.....||
Zfish   380 KGLDHDIALMKLAQPLTFNGMVE---------PICLPNFGEQFEDGKMCWISGWG-ATEDGGDAS 434

  Fly   192 LQQ--APVPILNKELCQ--VIYK--LPASQMCAGFLQGGIDACQGDSGGPLICDG----RLAGII 246
            :.|  |.||:::.:.|.  .:|:  |.|..:|||:|.||.|:|||||||||.|:.    :|.|..
Zfish   435 VSQHCASVPLISNKACSQPEVYQGYLTAGMICAGYLDGGTDSCQGDSGGPLACEDSSIWKLVGAT 499

  Fly   247 SWGVGCADPGYPGVYTNVSHFLKWIRRANASLDYSEYRQIPPLNLAS 293
            |||.|||:...|||||.::..|.||.     |.......:.||.::|
Zfish   500 SWGQGCAEKNKPGVYTRITQSLTWIH-----LQMEREEILHPLTVSS 541

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32755	NP_727055.1	Tryp_SPc	37..271	CDD:214473	89/254 (35%)
CG32755	NP_727055.1	Tryp_SPc	38..273	CDD:238113	91/255 (36%)
tmprss3a	XP_021334565.1	LDLa	154..186	CDD:238060
		SRCR_2	191..292	CDD:317845	7/23 (30%)
		Tryp_SPc	298..525	CDD:238113	90/254 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910