DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32751 and CG32750

DIOPT Version :9

Sequence 1:	NP_001284927.1	Gene:	CG32751 / 318189	FlyBaseID:	FBgn0052751	Length:	525	Species:	Drosophila melanogaster
Sequence 2:	NP_727067.1	Gene:	CG32750 / 326238	FlyBaseID:	FBgn0052750	Length:	523	Species:	Drosophila melanogaster

Alignment Length:	531	Identity:	201/531 - (37%)
Similarity:	290/531 - (54%)	Gaps:	65/531 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 FLFCLALGLMLNLSQQASLFKRDFYTAGVVEFEPS-------NELSDNLAGYLEIIQSQNATSTD 66
            ||:.::..|:|.   ..:..:..||.|||||:.|:       ..|..||||||||:.|.|.| ||
  Fly     8 FLWLISFTLVLT---DDNSVENKFYIAGVVEYRPTFMGGTSEQLLQANLAGYLEIMASGNGT-TD 68

  Fly    67 IIVFPESTLNSAGSTTFVPNPEDQINPCL----SDPNATYYEEFLVTLSCAARNASKYIVINLTE 127
            ||||||:||||..:.|.||...:| :.|.    .||...   .||.:|:||||....|:|:|:.|
  Fly    69 IIVFPEATLNSVITLTAVPKFTEQ-SLCEEQGDDDPEIA---PFLRSLACAAREYGTYLVVNVKE 129

  Fly   128 KQKCEDIPEDTRPCASNGLNVFNTNVVFDRQGVVVSRYRKVHLYGEPK-NSTFLPELSTFETDFG 191
            :...:...::|  |:|.|.::.||||||||||.|:|||||.:||.||. |.|..||::||.|||.
  Fly   130 RVSEQCTSDET--CSSRGYSIHNTNVVFDRQGAVISRYRKWNLYLEPSTNRTESPEIATFTTDFN 192

  Fly   192 VTFGHFICFDILFYTPAHQLIVEQGITDFVYPAMWFSQLPFLTVNGIFSSKAVQIQLGWSYANNV 256
            ||||||||||:||||||..|:.:.||...:...|:.|:|||||        |.|.|.||::||.|
  Fly   193 VTFGHFICFDMLFYTPAQDLVEQLGIRHVIVTKMFNSELPFLT--------ASQFQQGWAWANRV 249

  Fly   257 NLLAAGASDPIVGNSGSGIYHGRSGSLRSVMRQES--GERSIYVARVPKYRAKRRMKRDLKRQVA 319
            ||||:|.|.|..|.||||||.|:.|:|..:|..:.  |:|.:.:|:||         .|.:..:|
  Fly   250 NLLASGGSLPQGGISGSGIYAGQQGALARLMITDELVGQRKLLLAKVP---------LDPEEPIA 305

  Fly   320 TSSSFN-----------IKRDYLENFTSEELKIDAGKIGNLSQNLCHGGFCCHFDLAWRSLGKPS 373
            |.....           :::..|:|||:.||.:..|  .::.:.:|....||.|.:.|..    .
  Fly   306 TDEILEPEIMTPVKLKLLQQPELKNFTTWELPMVRG--SSVDKRICQEDLCCEFRVTWTL----E 364

  Fly   374 RNTSHYSYRVGIYEGWRNEKRLDVNYIRNCGVFTCSGNSIDDCGQLLPD---IQRPLVTFTHVEI 435
            .....|:||:|::.|.|..:....:.||.||:|.|.|.|::.||.:..:   :|...|.||.::|
  Fly   365 DTQPEYNYRLGVWVGQRRYEEEQYSAIRLCGLFACKGASVESCGLVSEEEVHLQDHRVVFTDLQI 429

  Fly   436 RVTYPQSREFLLFPDTL-LDNLLPLEPKQFEWSQKRISEESHQVRFALRKSLEVKHLLTFGIYGN 499
            ...:.:....|:.|.|| ..:...|:|.|..||.:.::..: :::..||:  ....|:||.||||
  Fly   430 LGEFVRRPRRLILPSTLSSSSFYALQPSQLAWSMEELANVT-RIKMELRQ--PHSQLMTFAIYGN 491

  Fly   500 YYNNECTFGVG 510
            |::.....|.|
  Fly   492 YFDEYANGGAG 502

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32751	NP_001284927.1	biotinidase_like	33..329	CDD:143591	142/320 (44%)
CG32751	NP_001284927.1	Vanin_C	324..503	CDD:408788	52/193 (27%)
CG32750	NP_727067.1	biotinidase_like	29..322	CDD:143591	142/316 (45%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45466613
Domainoid	1	1.000	107	1.000	Domainoid score	I6443
eggNOG	1	0.900	-	-		E1_COG0388
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	163	1.000	Inparanoid score	I4181
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1276751at2759
OrthoFinder	1	1.000	-	-		FOG0001380
OrthoInspector	1	1.000	-	-		otm26620
orthoMCL	1	0.900	-	-		OOG6_103493
Panther	1	1.100	-	-	P	PTHR10609
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X969
	11	10.800