DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32751 and Btnd

DIOPT Version :9

Sequence 1:	NP_001284927.1	Gene:	CG32751 / 318189	FlyBaseID:	FBgn0052751	Length:	525	Species:	Drosophila melanogaster
Sequence 2:	NP_572298.1	Gene:	Btnd / 31552	FlyBaseID:	FBgn0029848	Length:	553	Species:	Drosophila melanogaster

Alignment Length:	536	Identity:	201/536 - (37%)
Similarity:	274/536 - (51%)	Gaps:	79/536 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 LALGLMLNLSQQASLFKRDFYTAGVVEF------EPSNELSDNLAGYLEIIQSQNATSTDIIVFP 71
            |.|.::.:.|.|.|..:...|||.|||.      .|....:.....:.:||  :.....||||||
  Fly     9 LLLSVLFSSSHQLSKPEDPTYTAAVVEHSQPVGDSPRARTTSASESFQKII--REVGDVDIIVFP 71

  Fly    72 ESTLNSAGSTTFVPNPEDQINPCLSDPNATYYEEFLVTLSCAARNASKYIVINLTEKQKC-EDIP 135
            |..|||..:.||||:....|.||..    |.||.||:.|||:||....|:|||:.||:.| ....
  Fly    72 EHILNSQATATFVPHESQNITPCYQ----TDYELFLIELSCSARANHLYVVINVVEKELCAHGAG 132

  Fly   136 EDT-RPCASNGLNVFNTNVVFDRQGVVVSRYRKVHLYGEPKNSTFL---PELSTFETDFGVTFGH 196
            .|| .||.|:|:..|||||||||:|.:||||||.||:.....||.:   |::|.|.|||||||||
  Fly   133 SDTYNPCPSSGVRYFNTNVVFDRRGRIVSRYRKTHLWRHEYVSTSVLRSPDISIFRTDFGVTFGH 197

  Fly   197 FICFDILFYTPAHQLIVEQGITDFVYPAMWFSQLPFLTVNGIFSSKAVQIQLGWSYANNVNLLAA 261
            |||||:|||.||.:|:.|..|||.|||..|||:||||        .|||:|.||::.|:||:|||
  Fly   198 FICFDMLFYDPAMKLVKEHKITDIVYPTYWFSELPFL--------GAVQLQEGWAFGNDVNVLAA 254

  Fly   262 GASDPIVGNSGSGIYHGRSGSLRSVMRQESGERSIYVARVPK-------------YRAKRRMKRD 313
            .||:|....||||||.||.|.|.:.:.::...: :.:|.|||             :..:|:.:|
  Fly   255 DASNPDGRTSGSGIYAGRGGRLVAEIFEQPTTK-LLIAEVPKREHGQLAPTFTPIFEPQRKTQR- 317

  Fly   314 LKRQVATSSSFNIKRDYLENFTSEELKIDAGKIGNLSQNLCHGGFCCHFDLAWRSLGK-----PS 373
             ...:||....|:     :.|.||.|..|   ..:..:.||||.|||.|.:..:....     ||
  Fly   318 -LTGLATYRDNNV-----DIFESELLDDD---FLSFERQLCHGSFCCTFSIERKVTSAAENELPS 373

  Fly   374 RNTSHYSYRVGIYEGWRNEKR---LDVNYIRNCGVFTCSGNSIDDCGQLLPDIQRPLVT--FTHV 433
            .....|.||:|:|  |.||..   :|......|.:|.|:...:..||.:.|:.:..:.|  ||.:
  Fly   374 SGAKSYRYRIGVY--WGNETTVIGVDRTEQATCALFACTDVRLASCGYIYPENEEVINTHHFTKL 436

  Fly   434 EIRVTY---PQSREFLLFPDTLLDNLLPLEPKQFEWSQKRISEESHQVRFALRKSLEV------- 488
            .|...:   |:.|. |:.|.:|....||:....:||.      ||.:....|.|::.|
  Fly   437 SISGNFPAAPRGRR-LIMPSSLNALFLPVSVSDYEWI------ESPEAANNLDKTILVDLKLAKA 494

  Fly   489 -KHLLTFGIYGNYYNN 503
             ..||||.|:.|||.:
  Fly   495 QNDLLTFAIWANYYTD 510

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32751	NP_001284927.1	biotinidase_like	33..329	CDD:143591	140/319 (44%)
CG32751	NP_001284927.1	Vanin_C	324..503	CDD:408788	57/199 (29%)
Btnd	NP_572298.1	biotinidase_like	29..308	CDD:143591	135/293 (46%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45466615
Domainoid	1	1.000	107	1.000	Domainoid score	I6443
eggNOG	1	0.900	-	-		E1_COG0388
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	163	1.000	Inparanoid score	I4181
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1276751at2759
OrthoFinder	1	1.000	-	-		FOG0001380
OrthoInspector	1	1.000	-	-		otm26620
orthoMCL	1	0.900	-	-		OOG6_103493
Panther	1	1.100	-	-	P	PTHR10609
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X969
	11	10.800