DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32751 and Nit1

DIOPT Version :9

Sequence 1:	NP_001284927.1	Gene:	CG32751 / 318189	FlyBaseID:	FBgn0052751	Length:	525	Species:	Drosophila melanogaster
Sequence 2:	NP_872609.2	Gene:	Nit1 / 289222	RGDID:	727821	Length:	327	Species:	Rattus norvegicus

Alignment Length:	277	Identity:	55/277 - (19%)
Similarity:	98/277 - (35%)	Gaps:	93/277 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 GVVEFEPSNELSDNLAGY----LEIIQSQ-------NATSTDIIVFPESTLNSAGSTTFVPNPED 89
            |.:...|...||....||    :.::.:|       .::||..    |..|.:....|..||.::
  Rat     3 GFITRPPHQLLSLLCTGYRLPQISVLCTQPRPRAMAESSSTSW----ELPLVAVCQVTSTPNKQE 63

  Fly    90 QINPCLSDPNATYYEEFLVTLSC----------AARNASKYIVINLTEKQKCEDIPED------- 137
            ....|     |...:|.....:|          .|||.::.::::       |.:..|
  Rat    64 NFKTC-----AELVQEATRLGACLAFLPEAFDFIARNPAETLLLS-------EPLDGDLLGQYSQ 116

  Fly   138 -TRPC----ASNGLN-----------VFNTNVVFDRQGVVVSRYRKVHL-------YGEPKNSTF 179
             .|.|    :..|.:           ::|.:|:.:.:|.||:.|||.||       .|..:.|.:
  Rat   117 LARECGIWLSLGGFHERGQDWEQTQKIYNCHVLLNSKGSVVASYRKTHLCDVEIPGQGPMRESNY 181

  Fly   180 L-------PELSTFETDFGVTFGHFICFDILFYTPAHQL-IVEQGITDFVYPAMWFSQLPFLTVN 236
            .       |.:.|.....|:.    ||:|:.|  |...| :.:.|.....||:      .|.:|.
  Rat   182 TMPGYALEPPVKTPAGKVGLA----ICYDMRF--PELSLKLAQAGAEILTYPS------AFGSVT 234

  Fly   237 G------IFSSKAVQIQ 247
            |      :..::|::.|
  Rat   235 GPAHWEVLLRARAIESQ 251

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32751	NP_001284927.1	biotinidase_like	33..329	CDD:143591	55/277 (20%)
CG32751	NP_001284927.1	Vanin_C	324..503	CDD:408788
Nit1	NP_872609.2	nit	49..316	CDD:143596	45/227 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0388
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900