Protein Alignment CG32751 and Btd

DIOPT Version :9

• Sequence 1: NP_001284927.1
• Gene: CG32751 / 318189
• FlyBaseID: FBgn0052751
• Length: 525
• Species: Drosophila melanogaster
• Sequence 2: NP_079571.1
• Gene: Btd / 26363
• MGIID: 1347001
• Length: 529
• Species: Mus musculus
• Alignment Length: 558
• Identity: 159/558 - (28%)
• Similarity: 228/558 - (40%)
• Gaps: 109/558 - (19%)

  Fly     8 FFLFCLALGLMLNLSQQASLFKRDFYTAGVVEF---------------EPSNELSDNLAGYLEII 57
            |||.|.||.|.::.:.|... :.::|.|.|.|.               |....:..||..|.:.:
Mouse    20 FFLGCSALALGVSSASQEHR-EAEYYVAAVYEHPSVLSPNPLELVSRQEALELMKQNLDVYEQQV 83

  Fly    58 QSQNATSTDIIVFPESTLNSAGST--------TFVPNPE-DQINPCLSDPNATYYEEFLVTLSCA 113
            .:.......||||||..::....|        .|:|:|: .:.|||| :|......|.|..|||.
Mouse    84 MAAAQKGVQIIVFPEDGIHGFNFTRTSIYPFLDFMPSPKLVRWNPCL-EPFRFNDTEVLQRLSCM 147

  Fly   114 ARNASKYIVINLTEKQKCEDIPEDTRPCASNGLNVFNTNVVFDRQGVVVSRYRKVHLYGE----- 173
            |.....::|.||..||.|  :..|. .|..:|...|||||||...|.:|.||||.:||.|
Mouse   148 AIKGGMFLVANLGTKQPC--LSSDP-GCPQDGRYQFNTNVVFSDNGTLVDRYRKHNLYFEAAFDT 209

  Fly   174 PKNSTFLPELSTFETDFGVTFGHFICFDILFYTPAHQLIVEQGITDFVYPAMWFSQLPFLTVNGI 238
            |.|    .:|.||:|.|...||.|.||||||:.||.:|:.:..:...|||..|.:|||.|.
Mouse   210 PAN----VDLITFDTPFAGKFGVFTCFDILFFDPAVRLLRDFEVKHIVYPTAWMNQLPLLA---- 266

  Fly   239 FSSKAVQIQLGWSYANNVNLLAAGASDPIVGNSGSGI--------YH------------------ 277
                |::||..::.|..||:|||....|.:|.:||||        ||
Mouse   267 ----AIEIQKAFATAFGVNVLAANIHHPTLGMTGSGIHTPLKSFWYHDMDDPKGHLIIAQVATNP 327

  Fly   278 -GRSGSLRSVMRQESGERS-IYVARVPKYRAKRRMK----RDLKRQVATSSSFNIKRDYLENFTS 336
             |.:|:..:....:...|. :.:.....|..|...:    ...|..|....:|:.:..| :|||
Mouse   328 QGLTGTGNTTSEMDPSHRKFLKILSGDPYCEKDAQEVHCDEAAKWNVNVPPTFHSEMMY-DNFT- 390

  Fly   337 EELKIDAGKIGNLSQNLCHGGFCCHFDLAWRSLGKPSRNTSHYSYRVGIYEGWRNEKRLDVNYIR 401
              |....|..|:|  .:|....|||......:|.|.       .|.:|:::|.....  ...||:
Mouse   391 --LVPVWGTEGHL--QVCSNSLCCHLLYERPTLSKE-------LYALGVFDGLHTVH--GTYYIQ 442

  Fly   402 NCGVFTCSGNSIDDCGQLLPDIQRPLVTFTHVEIRVTYPQSREFLLFPDTLLDNLLPLEPKQFEW 466
            .|.:..|.|...|.|||.:.:.: .|..| |:     :.......:||..|...:....|.|..|
Mouse   443 TCALVKCGGLGFDTCGQEITEAE-GLFDF-HL-----WGNFSTLYIFPLFLTSGMTLDTPDQLGW 500

  Fly   467 SQKRISEESHQVRFALRKSLEVKHLLTFGIYGNYYNNE 504
                  |..|   :.|||......|:|..:||..|..:
Mouse   501 ------ENDH---YFLRKRGLSSGLVTAALYGRLYERK 529

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG32751	NP_001284927.1	biotinidase_like	33..329	CDD:143591	106/356 (30%)
		Vanin_C	324..503	CDD:408788	46/178 (26%)
Btd	NP_079571.1	biotinidase_like	44..347	CDD:143591	101/318 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167847839
Domainoid	1	1.000	96	1.000	Domainoid score	I7293
eggNOG	1	0.900	-	-		E1_COG0388
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H37255
Inparanoid	1	1.050	165	1.000	Inparanoid score	I4179
Isobase	1	0.950	-	0.918296	Normalized mean entropy	S7850
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1276751at2759
OrthoFinder	1	1.000	-	-		FOG0001380
OrthoInspector	1	1.000	-	-		mtm8847
orthoMCL	1	0.900	-	-		OOG6_103493
Panther	1	1.100	-	-	O	PTHR10609
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X969
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	15	14.710