DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rbm13 and MAK16

DIOPT Version :9

Sequence 1:	NP_001285026.1	Gene:	Rbm13 / 31818	FlyBaseID:	FBgn0030067	Length:	343	Species:	Drosophila melanogaster
Sequence 2:	NP_115898.2	Gene:	MAK16 / 84549	HGNCID:	13703	Length:	300	Species:	Homo sapiens

Alignment Length:	353	Identity:	165/353 - (46%)
Similarity:	217/353 - (61%)	Gaps:	72/353 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MQHDDVVWSII-NKSFCSHKVKTDTRTFCRHEYNLTGLCTRRTCPLANSQYATVREEKGIIYLFI 64
            ||.|||:|..: ||.|||.|::|.|::|||:||:|||||.|.:||||||||||::||||..||::
Human     1 MQSDDVIWDTLGNKQFCSFKIRTKTQSFCRNEYSLTGLCNRSSCPLANSQYATIKEEKGQCYLYM 65

  Fly    65 KTAERAHMPSKLWERIKLSRNFEKAIEQINENLVFWPKYMIAKNKQRFLKITQYLIRMRRLKLRR 129
            |..|||..|.:||||::||:|:|||:|||:|||::||:::..|.||||.||||||||:|:|.|:|
Human    66 KVIERAAFPRRLWERVRLSKNYEKALEQIDENLIYWPRFIRHKCKQRFTKITQYLIRIRKLTLKR 130

  Fly   130 QKLIVPLSTKIERREARREEKALVAAKIDNHIEKALMDRLKNGTYRDIYNFSQTAFNKALEAERV 194
            |:.:||||.|:||||.|||||||:||::||.|||.|::|||..||.|||||...||:||||
Human   131 QRKLVPLSKKVERREKRREEKALIAAQLDNAIEKELLERLKQDTYGDIYNFPIHAFDKALE---- 191

  Fly   195 DEDDEEELDDEDENEEQLEREMEVDGDDSREAEEVQRSLLDEEFVEADTDDEEEDDDDDDDDDED 259
                                                     ::..|:|:.|.||.||||||::
Human   192 -----------------------------------------QQEAESDSSDTEEKDDDDDDEE-- 213

  Fly   260 DYDSDSGKREEVEVG-------SDFEE-------SDEDDDADADDIEETKVPAKKTASKAKKDKK 310
                |.||||.||.|       ||||:       ||||.|..:...||    .:|..|...|.|.
Human   214 ----DVGKREFVEDGEVDESDISDFEDMDKLDASSDEDQDGKSSSEEE----EEKALSAKHKGKM 270

  Fly   311 SPAGNSRRSRSKPKLQLEYEYEVEKEAQ 338
            ...|..:|.|:  .:::|||.|.|..|:
Human   271 PLRGPLQRKRA--YVEIEYEQETEPVAK 296

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rbm13	NP_001285026.1	PLN00040	1..225	CDD:215038	122/224 (54%)
		Ribosomal_L28e	6..115	CDD:280030	65/109 (60%)
		Mak16	139..241	CDD:282698	36/101 (36%)
MAK16	NP_115898.2	PLN00040	1..196	CDD:215038	122/239 (51%)
MAK16	NP_115898.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	191..278		36/141 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165144348
Domainoid	1	1.000	162	1.000	Domainoid score	I4001
eggNOG	1	0.900	-	-		E1_COG5129
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	295	1.000	Inparanoid score	I2764
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54003
OrthoDB	1	1.010	-	-		D1394336at2759
OrthoFinder	1	1.000	-	-		FOG0004909
OrthoInspector	1	1.000	-	-		oto91801
orthoMCL	1	0.900	-	-		OOG6_102084
Panther	1	1.100	-	-	LDO	PTHR23405
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X3461
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	14	13.770