DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Uros1 and Uros

DIOPT Version :9

Sequence 1:	NP_001259362.1	Gene:	Uros1 / 31817	FlyBaseID:	FBgn0030066	Length:	277	Species:	Drosophila melanogaster
Sequence 2:	NP_001289014.1	Gene:	Uros / 22276	MGIID:	98917	Length:	265	Species:	Mus musculus

Alignment Length:	265	Identity:	95/265 - (35%)
Similarity:	130/265 - (49%)	Gaps:	22/265 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 VIIFKSESESS---DVYAETLEKHDFNPVFVPTLSFGFKNLDELRAKLQNPDKYAGIIFTSPRCV 69
            |::.|...|..   |.|.:.|.........:|.|||.|.:|..|..||.:|:.:.|:||||||.|
Mouse     3 VLLLKDAKEDDSGLDPYIQELRLCGLEATLIPVLSFEFMSLPSLSEKLSHPEGFGGLIFTSPRAV 67

  Fly    70 EAV---AESLNLGE-----LPGGWKMLHNYAVGEVTHNLALST-LDQLFTHGKQTGNARALGDYI 125
            |||   .|..|..|     |...|.....|.||..|.:|.... ||   ..|..:|||..|.:||
Mouse    68 EAVKLCLEKDNKTEAWEKSLKDRWNAKSVYVVGSATASLVNKIGLD---AEGAGSGNAEKLAEYI 129

  Fly   126 VDTFDGSRALPLLLPCGNLATDTLLSKLAENGFSVDACEVYETRCHPELGANVERALEIYGESIE 190
            ..  ..|..||||.|||.:..|||...|.:.|..:::..||:|..||.:..:::...|..|....
Mouse   130 CS--KPSSELPLLFPCGTIKGDTLPKMLKDKGIPMESMHVYQTVPHPGIQGSLKSYYEDQGIPAS 192

  Fly   191 FLAFFSPSGVNCAQQYFTSRQ-LSMDKWKLVAIGPSTRRALESLGQKVYCTAERPTVEHL---VK 251
             :.||||||:..:.:|..:.. .|.|:.|.:||||||.||:.:.|..|.||||.||.:.|   ::
Mouse   193 -ITFFSPSGLKYSLEYIQALSGSSFDQIKFIAIGPSTTRAMAAKGLPVSCTAESPTPQALAAGIR 256

  Fly   252 VLLNP 256
            .:|.|
Mouse   257 NVLKP 261

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Uros1	NP_001259362.1	HEM4	20..251	CDD:280722	89/243 (37%)
Uros	NP_001289014.1	HemD	3..255	CDD:119440	93/257 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167840081
Domainoid	1	1.000	128	1.000	Domainoid score	I5299
eggNOG	1	0.900	-	-		E1_COG1587
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H37296
Inparanoid	1	1.050	133	1.000	Inparanoid score	I4581
Isobase	1	0.950	-	0	Normalized mean entropy	S4099
OMA	1	1.010	-	-		QHG59256
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0005207
OrthoInspector	1	1.000	-	-		otm43609
orthoMCL	1	0.900	-	-		OOG6_104358
Panther	1	1.100	-	-	LDO	PTHR12390
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2144
SonicParanoid	1	1.000	-	-		X4829
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	16	15.740