DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Moe and inavaa

DIOPT Version :9

Sequence 1:	NP_727290.1	Gene:	Moe / 31816	FlyBaseID:	FBgn0011661	Length:	649	Species:	Drosophila melanogaster
Sequence 2:	XP_009302242.1	Gene:	inavaa / 567844	ZFINID:	ZDB-GENE-081105-161	Length:	596	Species:	Danio rerio

Alignment Length:	259	Identity:	56/259 - (21%)
Similarity:	94/259 - (36%)	Gaps:	78/259 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   369 PD--TIDVQQMKAQAREEKNAKQQEREKLQLALAARERAEKKQQEYEDRLKQMQEDMERSQRDLL 431
            ||  |..|:::....|..:..:|...::|:|.:...::...::.|...:|.        |...||
Zfish    22 PDSPTSPVKELNTHTRAMRLKQQALEDRLELCVLELKKLCIREAELTGKLP--------SDYPLL 78

  Fly   432 --EAQDMIRR-------LEEQLKQLQAAKDELELRQKELQAMLQRLEEAKNMEAVEKLKLEEEIM 487
              |....:||       |:|..  :....:|.||...|....|||    :..||..||.|||.|
Zfish    79 PDEKPPQVRRRIGAAFKLDEGF--ISQDGEESELLSLEADLALQR----QIYEAARKLSLEEHI- 136

  Fly   488 AKQMEVQRIQDEVNAKDEETKRLQDEV--------------------------EDARRKQVIA-- 524
            :|.:...|:| :...::::.|.||..:                          :|:.....:|
Zfish   137 SKPVRKSRLQ-QCKREEKKLKELQVAILKHRINHGCVSPQTCYSSRQRDLCMSDDSSLSDAVALD 200

  Fly   525 -----AEAAAALLAASTTPQHHHVAEDENENEEELT----NGDAGGDVSRDLDTDEHIKDPIED 579
                 |..:.|:|.:||           :...:.||    ||......|..||.|   ..||::
Zfish   201 DDSDSAPFSPAVLGSST-----------DSGFQRLTLLPKNGPKQSSSSSSLDYD---ASPIQN 250

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Moe	NP_727290.1	B41	26..278	CDD:214604
		FERM_N	28..83	CDD:286467
		FERM_M	163..278	CDD:278785
		FERM_C_ERM	272..368	CDD:270015
		GBP_C	<375..497	CDD:303769	31/130 (24%)
		ERM	403..649	CDD:279153	48/223 (22%)
		coiled coil	464..477	CDD:293879	4/12 (33%)
		coiled coil	486..497	CDD:293879	3/10 (30%)
inavaa	XP_009302242.1	DUF3338	4..138	CDD:314652	33/130 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3529
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900