DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32679 and vap-2

DIOPT Version :9

Sequence 1:	NP_727412.2	Gene:	CG32679 / 318150	FlyBaseID:	FBgn0052679	Length:	254	Species:	Drosophila melanogaster
Sequence 2:	NP_001300377.1	Gene:	vap-2 / 181273	WormBaseID:	WBGene00011462	Length:	507	Species:	Caenorhabditis elegans

Alignment Length:	256	Identity:	70/256 - (27%)
Similarity:	100/256 - (39%)	Gaps:	63/256 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 FTFAQNYC-DPE-LC--PS-----GRHVACQNSGRFVSGCSGEFVQVDAHIPLILQLHNERRNLI 75
            ||:..:.| .|| ||  ||     |....|.||  .||..:..|.         |:.||..|:.:
Worm   277 FTYPGSKCLVPEGLCQAPSMVKDDGGSFQCDNS--LVSDVTRNFT---------LEQHNFYRSRL 330

  Fly    76 AGGGVSGF----------PSAVQMATMSWDTTLAQLA---AYNALQCRMAHDECRNTNTYRYAGQ 127
            |    .||          |.|.||..|.:|..|.:.|   |.|.:....||.|..|      .||
Worm   331 A----KGFEWNGETNTSQPKASQMIKMEYDCMLERFAQNWANNCVFAHSAHYERPN------QGQ 385

  Fly   128 NLSILFTRSVDVAVFLRQRIAAWFDENRD-------ATSGDMEDYQMRGGPAIGHFTTMVNERNN 185
            ||.:....:.|....:...:..|:.|..:       ..:.::.|.:   |.||||:|.|..:|..
Worm   386 NLYMSSFSNPDPRSLIHTAVEKWWQELEEFGTPIDNVLTPELWDLK---GKAIGHYTQMAWDRTY 447

  Fly   186 RVGCAIARFTDANNVQATLLACNYA-VTNVVNNPVYRAGTAA---SECTTGRN-SNYPNLC 241
            |:||.|     ||..:.:.:.|:|. ..|..||.:|..|...   .:|..|.: ....:||
Worm   448 RLGCGI-----ANCPKMSYVVCHYGPAGNRKNNKIYEIGDPCEVDDDCPIGTDCEKTTSLC 503

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32679	NP_727412.2	SCP_euk	63..210	CDD:240180	44/166 (27%)
vap-2	NP_001300377.1	SCP	104..253	CDD:214553
vap-2	NP_001300377.1	SCP	315..468	CDD:214553	46/179 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2340
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1528782at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10334
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X35
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.920