DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rab9D and RAB1A

DIOPT Version :9

Sequence 1:	NP_727432.1	Gene:	Rab9D / 318149	FlyBaseID:	FBgn0067052	Length:	197	Species:	Drosophila melanogaster
Sequence 2:	NP_004152.1	Gene:	RAB1A / 5861	HGNCID:	9758	Length:	205	Species:	Homo sapiens

Alignment Length:	170	Identity:	70/170 - (41%)
Similarity:	106/170 - (62%)	Gaps:	6/170 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 QYDNPFKIILLGDSGVGKTCLLMRFSDNQFTTRHRSTVGLDRRECSVEFADWRMGR--MLQVWDT 65
            :||..||::|:|||||||:|||:||:|:.:|..:.||:|:|.:..::|..    |:  .||:|||
Human     7 EYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELD----GKTIKLQIWDT 67

  Fly    66 SDDERFKLLKATQCRSAHGILLVYDITSSKSFQNIDGWMKEIRRLCPDKVIVLLVGNKSDDPNHR 130
            :..|||:.:.::..|.||||::|||:|..:||.|:..|::||.|...:.|..||||||.|....:
Human    68 AGQERFRTITSSYYRGAHGIIVVYDVTDQESFNNVKQWLQEIDRYASENVNKLLVGNKCDLTTKK 132

  Fly   131 QVSMAQGFNYAHRQSICFEEVSAKSGRNVYDIFSSLAMDI 170
            .|.......:|....|.|.|.|||:..||...|.::|.:|
Human   133 VVDYTTAKEFADSLGIPFLETSAKNATNVEQSFMTMAAEI 172

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rab9D	NP_727432.1	RAB	8..171	CDD:197555	68/165 (41%)
Rab9D	NP_727432.1	Rab	8..167	CDD:206640	66/160 (41%)
RAB1A	NP_004152.1	Rab1_Ypt1	10..175	CDD:206661	68/167 (41%)
		Effector region. /evidence=ECO:0000255	40..48		3/7 (43%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	178..205
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0084
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1149105at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820