Protein Alignment Rab9D and RAB35

DIOPT Version :10

• Sequence 1: NP_727432.1
• Gene: Rab9D / 318149
• FlyBaseID: FBgn0067052
• Length: 197
• Species: Drosophila melanogaster
• Sequence 2: NP_006852.1
• Gene: RAB35 / 11021
• HGNCID: 9774
• Length: 201
• Species: Homo sapiens
• Alignment Length: 163
• Identity: 67/163 - (41%)
• Similarity: 108/163 - (66%)
• Gaps: 3/163 - (1%)

  Fly     4 YDNPFKIILLGDSGVGKTCLLMRFSDNQFTTRHRSTVGLDRRECSVEFADWRMGRMLQVWDTSDD 68
            ||:.||::::|||||||:.||:||:||.|:..:.:|:|:|.:..:||....::  .||:|||:..
Human     5 YDHLFKLLIIGDSGVGKSSLLLRFADNTFSGSYITTIGVDFKIRTVEINGEKV--KLQIWDTAGQ 67

  Fly    69 ERFKLLKATQCRSAHGILLVYDITSSKSFQNIDGWMKEIRRLCPDKVIVLLVGNKSDDPNHRQVS 133
            |||:.:.:|..|..||:::|||:||::||.|:..|:.||.:.| |.|..:|||||:|||..:.|.
Human    68 ERFRTITSTYYRGTHGVIVVYDVTSAESFVNVKRWLHEINQNC-DDVCRILVGNKNDDPERKVVE 131

  Fly   134 MAQGFNYAHRQSICFEEVSAKSGRNVYDIFSSL 166
            ....:.:|.:..|...|.|||...||.::|:.:
Human   132 TEDAYKFAGQMGIQLFETSAKENVNVEEMFNCI 164

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab9D	NP_727432.1	Rab	8..167	CDD:206640	65/159 (41%)
RAB35	NP_006852.1	Rab35	3..201	CDD:133310	67/163 (41%)
		Switch 1. /evidence=ECO:0000269|PubMed:30905672, ECO:0007744|PDB:6IF2, ECO:0007744|PDB:6IF3	30..42		4/11 (36%)
		Switch 2. /evidence=ECO:0000269|PubMed:30905672, ECO:0007744|PDB:6IF2, ECO:0007744|PDB:6IF3	64..80		5/15 (33%)