DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rab9E and RAB8B

DIOPT Version :9

Sequence 1:	NP_727438.1	Gene:	Rab9E / 318148	FlyBaseID:	FBgn0052673	Length:	197	Species:	Drosophila melanogaster
Sequence 2:	NP_057614.1	Gene:	RAB8B / 51762	HGNCID:	30273	Length:	207	Species:	Homo sapiens

Alignment Length:	169	Identity:	76/169 - (44%)
Similarity:	105/169 - (62%)	Gaps:	2/169 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 YDNPFKIIILGDSGVGKTCLLMRFSDNQFTTRHRSTLGMDRRECSVEFADWRMGRMLQVWDTSDD 68
            ||..||::::|||||||||||.|||::.|.|...||:|:|.:..::|....::  .||:|||:..
Human     5 YDYLFKLLLIGDSGVGKTCLLFRFSEDAFNTTFISTIGIDFKIRTIELDGKKI--KLQIWDTAGQ 67

  Fly    69 ERFKLLKATHCRSAHGILLVYDITSSKSFQNIDGWMKEIRRLCPDKVIVLLVGNKSDDPNHRQVS 133
            |||:.:...:.|.|.||:||||||:.|||.||..|::.|.......|..:::|||.|..:.||||
Human    68 ERFRTITTAYYRGAMGIMLVYDITNEKSFDNIKNWIRNIEEHASSDVERMILGNKCDMNDKRQVS 132

  Fly   134 MAQGFNYAHRQSICFEEVSAKSGRNVYDIFSSLAMDIYT 172
            ..:|...|....|.|.|.||||..||.:.|.:||.||.|
Human   133 KERGEKLAIDYGIKFLETSAKSSANVEEAFFTLARDIMT 171

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rab9E	NP_727438.1	RAB	8..171	CDD:197555	72/162 (44%)
Rab9E	NP_727438.1	Rab	8..167	CDD:206640	69/158 (44%)
RAB8B	NP_057614.1	Rab8_Rab10_Rab13_like	6..172	CDD:206659	75/168 (45%)
RAB8B	NP_057614.1	Effector region. /evidence=ECO:0000250	37..45		3/7 (43%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910