DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rab9E and rab13

DIOPT Version :9

Sequence 1:	NP_727438.1	Gene:	Rab9E / 318148	FlyBaseID:	FBgn0052673	Length:	197	Species:	Drosophila melanogaster
Sequence 2:	NP_958486.1	Gene:	rab13 / 373105	ZFINID:	ZDB-GENE-030826-30	Length:	200	Species:	Danio rerio

Alignment Length:	168	Identity:	76/168 - (45%)
Similarity:	107/168 - (63%)	Gaps:	2/168 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 QYDNPFKIIILGDSGVGKTCLLMRFSDNQFTTRHRSTLGMDRRECSVEFADWRMGRMLQVWDTSD 67
            :||..||::::||||||||||::||:::.|.:.:.||:|:|.:..::|....::  .||||||:.
Zfish     4 KYDFLFKLLLIGDSGVGKTCLIIRFAEDNFNSTYISTIGIDFKVKTIEVEGKKV--KLQVWDTAG 66

  Fly    68 DERFKLLKATHCRSAHGILLVYDITSSKSFQNIDGWMKEIRRLCPDKVIVLLVGNKSDDPNHRQV 132
            .||||.:...:.|.|.||:||||||..||::||..|||.|:......|..:|:|||.|....|:|
Zfish    67 QERFKTITTAYYRGAMGIILVYDITDEKSYENIQNWMKSIKENASAGVSRMLLGNKCDIEAKRKV 131

  Fly   133 SMAQGFNYAHRQSICFEEVSAKSGRNVYDIFSSLAMDI 170
            |...|...|....|.|.|.||||..||.:.|:|||.||
Zfish   132 SKETGEKLAKEHGIRFFETSAKSSINVEESFTSLARDI 169

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rab9E	NP_727438.1	RAB	8..171	CDD:197555	74/163 (45%)
Rab9E	NP_727438.1	Rab	8..167	CDD:206640	70/158 (44%)
rab13	NP_958486.1	Rab8_Rab10_Rab13_like	6..172	CDD:206659	75/166 (45%)
		RAB	9..170	CDD:197555	74/163 (45%)
		Effector region. /evidence=ECO:0000250	37..45		3/7 (43%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	173..195
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910