DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Rab9E and Rab19

DIOPT Version :9

Sequence 1:	NP_727438.1	Gene:	Rab9E / 318148	FlyBaseID:	FBgn0052673	Length:	197	Species:	Drosophila melanogaster
Sequence 2:	NP_035356.1	Gene:	Rab19 / 19331	MGIID:	103292	Length:	217	Species:	Mus musculus

Alignment Length:	174	Identity:	57/174 - (32%)
Similarity:	99/174 - (56%)	Gaps:	3/174 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 DNPFKIIILGDSGVGKTCLLMRFSDNQFTTRHRSTLGMDRRECSVEFADWRMGRMLQVWDTSDDE 69
            |..||:|::|||.|||||::..|....::...::|:|:|....|:|. |.:..:| |||||:..|
Mouse    15 DYLFKVILIGDSNVGKTCVVQHFKSGVYSESQQNTIGVDFTVRSLEI-DGKKVKM-QVWDTAGQE 77

  Fly    70 RFKLLKATHCRSAHGILLVYDITSSKSFQNIDGWMKEIRRLCPDKVIVLLVGNKSDDPNHRQVSM 134
            ||:.:..::.||||..::.||:|...:|:::..|:.||.:.....::::|:|||||....|.|..
Mouse    78 RFRTITQSYYRSAHAAIIAYDLTRRSTFESVPHWIHEIEKYGAANLVIMLIGNKSDLWEKRHVLF 142

  Fly   135 AQGFNYAHRQS-ICFEEVSAKSGRNVYDIFSSLAMDIYTYRRVH 177
            ......|.:.. :...|.|||..||:.::|..:|.::.....:|
Mouse   143 EDACTLAEKHGLLAVLETSAKESRNIDEVFVLMAKELIARNSLH 186

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rab9E	NP_727438.1	RAB	8..171	CDD:197555	55/163 (34%)
Rab9E	NP_727438.1	Rab	8..167	CDD:206640	54/159 (34%)
Rab19	NP_035356.1	Rab19	15..179	CDD:133267	56/165 (34%)
		RAB	18..182	CDD:197555	55/165 (33%)
		Effector region. /evidence=ECO:0000250	46..54		2/7 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0084
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	3	2.860