DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rab9E and Rab1b

DIOPT Version :9

Sequence 1:	NP_727438.1	Gene:	Rab9E / 318148	FlyBaseID:	FBgn0052673	Length:	197	Species:	Drosophila melanogaster
Sequence 2:	NP_001103449.1	Gene:	Rab1b / 100126191	RGDID:	1642882	Length:	201	Species:	Rattus norvegicus

Alignment Length:	170	Identity:	68/170 - (40%)
Similarity:	108/170 - (63%)	Gaps:	6/170 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 QYDNPFKIIILGDSGVGKTCLLMRFSDNQFTTRHRSTLGMDRRECSVEFADWRMGR--MLQVWDT 65
            :||..||::::|||||||:|||:||:|:.:|..:.||:|:|.:..::|..    |:  .||:|||
  Rat     4 EYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELD----GKTIKLQIWDT 64

  Fly    66 SDDERFKLLKATHCRSAHGILLVYDITSSKSFQNIDGWMKEIRRLCPDKVIVLLVGNKSDDPNHR 130
            :..|||:.:.:::.|.||||::|||:|..:|:.|:..|::||.|...:.|..||||||||....:
  Rat    65 AGQERFRTITSSYYRGAHGIIVVYDVTDQESYANVKQWLQEIDRYASENVNKLLVGNKSDLTTKK 129

  Fly   131 QVSMAQGFNYAHRQSICFEEVSAKSGRNVYDIFSSLAMDI 170
            .|.......:|....:.|.|.|||:..||...|.::|.:|
  Rat   130 VVDNTTAKEFADSLGVPFLETSAKNATNVEQAFMTMAAEI 169

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rab9E	NP_727438.1	RAB	8..171	CDD:197555	66/165 (40%)
Rab9E	NP_727438.1	Rab	8..167	CDD:206640	64/160 (40%)
Rab1b	NP_001103449.1	Rab1_Ypt1	7..172	CDD:206661	66/167 (40%)
		Effector region. /evidence=ECO:0000255	37..45		3/7 (43%)
		Switch 2 region, required for interaction with REP1/CHM. /evidence=ECO:0000250\|UniProtKB:Q9H0U4	64..83		6/18 (33%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	173..201
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910