Protein Alignment CG32668 and pkp4

DIOPT Version :10

• Sequence 1: NP_727502.1
• Gene: CG32668 / 318147
• FlyBaseID: FBgn0052668
• Length: 863
• Species: Drosophila melanogaster
• Sequence 2: XP_068078007.1
• Gene: pkp4 / 561566
• ZFINID: ZDB-GENE-120411-14
• Length: 1142
• Species: Danio rerio
• Alignment Length: 772
• Identity: 151/772 - (19%)
• Similarity: 227/772 - (29%)
• Gaps: 295/772 - (38%)

  Fly     5 LRRRSRSETRPQANPAEMAKQPADSDKSDRQQQLAKHHQMRHHQPHASEQSLNKLGLV--SSGTS 67
            |.|....|.:..||..|..:..|:|                   |.|:..|.::..|:  |:.:|
Zfish    51 LTRELEEERQIVANQLERCRLGAES-------------------PGAASDSSSEKSLLWRSAESS 96

  Fly    68 GMGRRKTSAELISEAKMFLGE------SVNAVPLLATGG--ARLVSTRRPITPRESGRVLYGKVA 124
            |.|..|.|....|......|:      .:..:.|..:.|  |...|:.:..:..:||   |.:|:
Zfish    97 GAGVSKPSDGCPSPTFGVRGQGSLYSPELEQISLRESEGSAANSRSSTQMNSYSDSG---YQEVS 158

  Fly   125 LAGRPPSAFSMRYLQNEKPSTPRQLPALSGSVSATP--MPTRNGALLCQSSTETLIELLKQHSGL 187
                       .|..|  ..|||:....|.|.|:.|  .||    |...|..|      .|.|..
Zfish   159 -----------GYYSN--TVTPRRSEGRSQSTSSAPSGSPT----LAMSSRAE------GQASAQ 200

  Fly   188 KDCSDETVQHINAILQE----LYTRVRKQERNYKRGFILGGLYGLVECTSPRVLLAVARVVLALR 248
            ...|...::.::::...    |||......|...| ..||..||....:.||.|.::
Zfish   201 VGSSGRVMRRVSSVPSRAPSPLYTPSPPASRQPLR-TSLGSPYGSPIVSEPRPLPSI-------- 256

  Fly   249 VTGSNLTGACKLIFKVARHEQHDALFHEHDVLELLIDGLGHASPLDEPEACIYAYGCIRFLTASS 313
            ..|:.|                                         |.|..:|
Zfish   257 FPGTTL-----------------------------------------PPASSHA----------- 269

  Fly   314 AQERDDALNRNWIGLETSGESQSLPIPALMPPALSA------------------ISTSLCPRKLT 360
                .|.|:.:::|...:|.......|.|:...::|                  ..:|...|...
Zfish   270 ----PDPLHSSYLGRHGNGTGSESGSPTLLRAGMTAQPQQYGTLGKHDTRAYESTHSSFGSRAYD 330

  Fly   361 GQQTLVSRLARHGAVELMILHLQMLNEAGATKRL----QGPPLHT------------LYQ----- 404
            ..:.:|  |:|..::.:..|||.:........:|    :.|..|.            |||
Zfish   331 IFERMV--LSRPDSLTVSYLHLGLQTSYSQNSQLGQDTRSPDCHVTPIYEDRTFQNPLYQSPTHG 393

  Fly   405 -LSAAMR------ALADVSQQQQRLQLQLQLACPHLIRAAEVSMGELEVQANVVRTLSVLSEDSD 462
             .|||.|      .|...:.|...|:.|..|          .|||.:...::..|.......||
Zfish   394 SQSAASRNNTGFGTLQRTTSQCSTLRYQRGL----------FSMGSMATHSDTYRPGHYRQADS- 447

  Fly   463 CCETLHNYAARIGLLLGPSCAGGGQWSERLLAVLSRLGYMLGNILAKHESARIQYFHNDVAMEY- 526
                  ||                          ||....|.|.:.:  |..|...|.| ..|:
Zfish   448 ------NY--------------------------SRHSAALDNAVTR--SPSIDSVHKD-PREFA 477

  Fly   527 -----LLNVLEQLNERSPSSVAHLDAQIKLIRVVANMSVNPEVGAGLGNVRSLGAVLLQLLSKTS 586
                 |..|:..|....||..|:..|.|:.: ...:..:..|| ..||.:|.    |:.||.
Zfish   478 WRDPELPEVIRMLQHHFPSVQANAAAYIQHL-CYGDNRIKAEV-CRLGGIRH----LVDLLD--- 533

  Fly   587 EELTKKKSPEQQELLHATLGALHNLCFYQDKQAAVQPLAEGSLQSLIDDLSASLAKVLGNCQTSV 651
                           |.||....|.|              |:|::|
Zfish   534 ---------------HKTLEVQRNAC--------------GALRNL------------------- 550

  Fly   652 TKVELARVLGNLTRNEQARRCFCAAGGLPLMVQQLTKQAAGQDYELRTCAIGVLVNL 708
                   |.|..|.:.:.  |...:||:|.:|:.|.|.   .|.|:|....|||.||
Zfish   551 -------VYGKATDDNKV--CVRNSGGIPALVRLLRKT---PDSEVRELVTGVLWNL 595

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG32668	NP_727502.1	armadillo repeat	571..611	CDD:293788	7/39 (18%)
		armadillo repeat	619..665	CDD:293788	5/45 (11%)
		armadillo repeat	670..708	CDD:293788	13/37 (35%)
pkp4	XP_068078007.1	Atrophin-1	72..>284	CDD:460830	59/321 (18%)
		PHA03247	<172..269	CDD:223021	28/156 (18%)
		armadillo repeat	483..508	CDD:293788	8/24 (33%)
		Arm	512..551	CDD:425727	16/101 (16%)
		armadillo repeat	516..552	CDD:293788	16/98 (16%)
		Arm	556..597	CDD:425727	16/45 (36%)
		armadillo repeat	560..595	CDD:293788	13/39 (33%)
		armadillo repeat	601..653	CDD:293788
		Arm	767..808	CDD:425727
		armadillo repeat	771..808	CDD:293788
		ARM	815..853	CDD:214547
		armadillo repeat	818..852	CDD:293788
		armadillo repeat	859..899	CDD:293788
		armadillo repeat	905..940	CDD:293788