DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32668 and ctnnd1

DIOPT Version :9

Sequence 1:	NP_727502.1	Gene:	CG32668 / 318147	FlyBaseID:	FBgn0052668	Length:	863	Species:	Drosophila melanogaster
Sequence 2:	XP_021332609.1	Gene:	ctnnd1 / 556726	ZFINID:	ZDB-GENE-110208-9	Length:	950	Species:	Danio rerio

Alignment Length:	663	Identity:	127/663 - (19%)
Similarity:	234/663 - (35%)	Gaps:	230/663 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly   291 SPLDEPEACIYAYGCIRFLTASSAQERDDALN-RNWIGLETSGESQSLPIPALMPPALSAISTSL 354
            |.||.|:..::...|......|..::.|:.:. :|..|:                |||..:....
Zfish   403 SMLDNPKKEVHYAACGALKNISYGRDPDNKIAIKNCDGI----------------PALVRLLRKT 451

  Fly   355 CPRKLTGQQT-LVSRLARHGAVELMI----LHL----QMLNEAGATKRLQG-----PPLHTLYQ- 404
            ..:.||...| .:..|:.|.:|::.|    ||.    .|:..:|..:..:|     .|.|..::
Zfish   452 RDQDLTDTITGTLWNLSSHDSVKMEIVDHALHALSDEVMVPHSGWERGNEGGEESCKPRHLEWET 516

  Fly   405 -LSAAMRALADVSQQQQRLQLQLQLACPHLIRAAEVSMGELEVQANVVRTLSVLSEDSDC----- 463
             |:.....|.:||.::...:.:|: .|..|:   :..|..::.|.|.....:.|.|:|.|
Zfish   517 ALTNTTGCLRNVSSERSEARRKLR-ECSGLV---DSLMYIVQSQINCKDVDNKLIENSVCLLRNL 577

  Fly   464 ----------CETLHNYAARIGLLLGP-SCAGGGQWSERLLAVLSRLGYMLGNILAKHESARIQY 517
                      ||   .|...|.:..|| ....||.:|.|                    ..:.::
Zfish   578 SYQVHREIPGCE---RYLESIPVNQGPLPSQKGGCFSSR--------------------KGKDEW 619

  Fly   518 F----HNDVAMEYLLNVLEQLNERSPSSVAHLDAQIKLIRVVANM---SVNPEV-GAGLGNVRSL 574
            |    ..|......:::.::   .:|:....|..|.:::||..::   |.||.| .|..|.|::|
Zfish   620 FSKGKREDDGTSDTIDIPKR---TTPAKGYELLFQPEVVRVYTSLLKESKNPSVLEAAAGAVQNL 681

  Fly   575 GA--------------------VLLQLLSKTSEELTKKKS---------PEQQELL--HATLGAL 608
            .|                    ::.:|||..::.:.:..|         ...:|||  ||....:
Zfish   682 CAGRWTYGRYIRATMRQEHGLPMMTELLSHGNDRVVRAMSGALRNLAIDARNRELLGKHAVPNLV 746

  Fly   609 HNLCFYQDKQAAVQPLAEGSLQSLIDDLSASLAKVLGNCQTSVTKVELARVLGNLTRNEQARRCF 673
            .||......|.| :.|:|.::.|::    :::|:|:|      :.|:.|:.|    |:.|.
Zfish   747 ANLPGGGQSQPA-RALSEETVVSVL----STMAEVVG------SSVDAAKTL----RSAQG---- 792

  Fly   674 CAAGGLPLMVQQLTKQAAGQDYELRTCAIGVLVNLLGDGEQRGPFLQLRGAELLSLL------LR 732
                     :::|                 ||:|...:...|    ::|||.|:..:      ||
Zfish   793 ---------IERL-----------------VLINKDSNRSDR----EVRGAGLVLQIVWGFKELR 827

  Fly   733 GSLEQEDW----FLANIVCQALWNLLIDGHCAANLCQSSNILDEVSDLLADYLDEDRLSPGDDDN 793
            .:||::.|    |:.|:             ...|..:|:...:|.:..|.|       ..|..|
Zfish   828 RTLEKDGWKKTDFMVNL-------------NPPNNTRSNGGYEESTLPLID-------RGGKQD- 871

  Fly   794 DNDEDDPEREAEDLDASDTDPEAHDALWEDFALVATDLLER---IQNNFDRQQQSLPQNA----- 850
                    ||.:.:..:|..|:|:..:         |...|   :.:..||..:..||..
Zfish   872 --------REKDMIPLNDIGPDAYSTI---------DQRGRRNTLDDTLDRSDRDAPQGGMYGER 919

  Fly   851 -------DNEDDN 856
                   |:.|:|
Zfish   920 RGSLPLLDSYDEN 932

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32668	NP_727502.1	armadillo repeat	571..611	CDD:293788	12/70 (17%)
		armadillo repeat	619..665	CDD:293788	10/45 (22%)
		armadillo repeat	670..708	CDD:293788	3/37 (8%)
ctnnd1	XP_021332609.1	armadillo repeat	356..381	CDD:293788
		Arm	385..424	CDD:278915	5/20 (25%)
		armadillo repeat	389..425	CDD:293788	5/21 (24%)
		ARM	428..469	CDD:214547	10/56 (18%)
		armadillo repeat	432..467	CDD:293788	8/50 (16%)
		armadillo repeat	474..528	CDD:293788	10/53 (19%)
		armadillo repeat	646..683	CDD:293788	12/36 (33%)
		Arm	647..683	CDD:278915	12/35 (34%)
		ARM	693..728	CDD:214547	4/34 (12%)
		armadillo repeat	693..727	CDD:293788	4/33 (12%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1048
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900