DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32668 and Arvcf

DIOPT Version :9

Sequence 1:	NP_727502.1	Gene:	CG32668 / 318147	FlyBaseID:	FBgn0052668	Length:	863	Species:	Drosophila melanogaster
Sequence 2:	NP_001124485.1	Gene:	Arvcf / 303798	RGDID:	1306655	Length:	973	Species:	Rattus norvegicus

Alignment Length:	340	Identity:	82/340 - (24%)
Similarity:	121/340 - (35%)	Gaps:	96/340 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   562 PEVGAGLGNVRSLGAVLLQLLSKTSEELTKKKSPEQQELLHATLGALHNLCFYQDKQAAVQPLAE 626
            ||.|      |.|.|..|:..:..:.||.:::.|                     ..||..|||:
  Rat   291 PEYG------RGLRARALEDTADDTGELVEERPP---------------------FPAATAPLAQ 328

  Fly   627 ---GSLQSL---------IDDL-------SASLAKVLGNCQTSV--TKVELARVLGNLT-RNEQA 669
               |||.||         :|..       ...|.:||...:..|  .|...|..|.:|. .||..
  Rat   329 PERGSLGSLDRVVRRSPSVDSTRKEPRWRDPELPEVLAMLRHPVDPVKANAAAYLQHLCFENEGI 393

  Fly   670 RRCFCAAGGLPLMVQQLTKQAAGQDYELRTCAIGVLVNLL--GDGEQRGPFLQLRGAELLSLLLR 732
            :|......||||:|..|....|    |:|..|.|.|.||.  .|.:.:.......|...|..|||
  Rat   394 KRRVRQLRGLPLLVALLDHPRA----EVRRRACGALRNLSYGRDADNKAAIRDCGGVPALVRLLR 454

  Fly   733 GSLEQEDWFLANIVCQALWNLLIDGHCAANLCQSSNILDEVSDLLADY----LDEDRLSPGDD-D 792
            .:.:.|   :..:|...||||              :..:.:..::.|:    |..:.:.|... :
  Rat   455 AARDNE---VRELVTGTLWNL--------------SSYEPLKMVIIDHGLQTLTHEVIVPHSGWE 502

  Fly   793 NDNDEDDPEREAEDL-----------DASDTDPEAHDALWEDFALVATDLLERIQNNFDRQQQSL 846
            .:.:||...|:||..           :.|....||...|.|...||.. ||..:|:...|
  Rat   503 REPNEDSKPRDAEWTTVFKNTSGCLRNVSSDGAEARRRLRECEGLVDA-LLHALQSAVGR----- 561

  Fly   847 PQNADNED-DNDVFI 860
             ::.||:. :|.|.|
  Rat   562 -KDTDNKSVENCVCI 575

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32668	NP_727502.1	armadillo repeat	571..611	CDD:293788	7/39 (18%)
		armadillo repeat	619..665	CDD:293788	19/67 (28%)
		armadillo repeat	670..708	CDD:293788	13/37 (35%)
Arvcf	NP_001124485.1	ARM	356..474	CDD:237987	37/138 (27%)
		HEAT_2	361..463	CDD:290374	32/108 (30%)
		armadillo repeat	361..386	CDD:293788	7/24 (29%)
		armadillo repeat	394..430	CDD:293788	15/39 (38%)
		armadillo repeat	437..472	CDD:293788	9/37 (24%)
		ARM	438..580	CDD:237987	35/162 (22%)
		armadillo repeat	479..530	CDD:293788	8/50 (16%)
		ARM	651..751	CDD:237987
		armadillo repeat	651..687	CDD:293788
		armadillo repeat	697..731	CDD:293788
		armadillo repeat	738..783	CDD:293788
		armadillo repeat	789..821	CDD:293788
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1048
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900