Protein Alignment CG32668 and Pkp4

DIOPT Version :10

• Sequence 1: NP_727502.1
• Gene: CG32668 / 318147
• FlyBaseID: FBgn0052668
• Length: 863
• Species: Drosophila melanogaster
• Sequence 2: XP_036016888.1
• Gene: Pkp4 / 227937
• MGIID: 109281
• Length: 1206
• Species: Mus musculus
• Alignment Length: 762
• Identity: 143/762 - (18%)
• Similarity: 240/762 - (31%)
• Gaps: 270/762 - (35%)

  Fly    18 NPAEMAKQPADSDKSDRQQQLAKHHQMRHHQPHASEQSLNKLGLV-----------SSGTS-GMG 70
            |.|:..:.|.....|:...:.::.......||..:.:::.::..|           |:|.| ..|
Mouse   170 NKADSRQHPFTGSTSNHVVRTSRAEGQTLVQPSVANRAMRRVSSVPSRAQSPSYVTSTGVSPSRG 234

  Fly    71 RRKTSAELISEAKMFLGESVNAVPLLATG-GARLVSTRRPITPRESGRVLYGKVAL-AGRPPSAF 133
            ..:||                    |.:| |:..|:..||:.|.     .|....| |.|..|.:
Mouse   235 SLRTS--------------------LGSGFGSPSVTDSRPLNPS-----AYSSSTLPAQRAASPY 274

  Fly   134 SMRYLQNEKPSTPRQLPALSGSVSATPMPTRNGALLCQSSTETLIELLKQHSGLKDCSDETVQHI 198
            |.|      |::|..:..: |||::......||.             :.|:        :|...:
Mouse   275 SQR------PASPTAVRRV-GSVTSRQTSNPNGP-------------VPQY--------QTTTRV 311

  Fly   199 NA--ILQELYTRVRKQERNYKRGFILGGLYGLVECTSPRVLLAVARVVLALRVTGSNLTGACKLI 261
            .:  .|.:..|||....:            |.|..:||:               .|.:|...:.:
Mouse   312 GSPLTLTDAQTRVASPSQ------------GQVGSSSPK---------------RSGMTAVPQHL 349

  Fly   262 FKVARHEQHDA-LF--HEHDVLELLIDGLGHASPLDEPEACIYAYGCIRFLTASSAQERDDALNR 323
            ....:...||. .|  .::|:.|.::                              ..|.|:|.
Mouse   350 GPSLQRTVHDMDQFGQQQYDIYERMV------------------------------PPRPDSLT- 383

  Fly   324 NWIGLETSGESQSLPIPALMPPALSAISTSLCPRKLTGQQTLVS---RLARHGAVELMILHLQML 385
               ||.:|..||.   ..|.....||:|..|....:...:|..|   |...||.||
Mouse   384 ---GLRSSYASQH---SQLGQELRSAVSPDLHITPIYEGRTYYSPVYRSPNHGTVE--------- 433

  Fly   386 NEAGATKRLQGPPLHTLYQL-SAAMRALADVSQQQQRLQLQ-----LQLAC-------PHLIRAA 437
                    |||... .||:. |..:..|...|.|:..|..|     |..|.       |...|..
Mouse   434 --------LQGSQT-ALYRTGSVGIGNLQRTSSQRSTLTYQRNNYALNTAATYAEPYRPVQYRVQ 489

  Fly   438 EVSMGELE----VQANVVRTLSVLSEDSD---------CCET---LHNYAARIGLLLGPSCAGGG 486
            |.|...|:    ......|:.|:.|...|         |.:|   ...:|
Mouse   490 ECSYNRLQHTGPADDGATRSPSIDSIQKDPSTLKGVIHCLQTSVVFWEFA--------------- 539

  Fly   487 QWSE-RLLAVLSRLGYMLGNILAKHESARIQYF---HNDVAME--------YLLNVLEQL----- 534
             |.: .|..|:..|.:...::.| :.:|.:|:.   .|.|.||        :|:::|:..
Mouse   540 -WRDPELPEVIHMLQHQFPSVQA-NAAAYLQHLCFGDNKVKMEVYRLGGIKHLVDLLDHRVLEVQ 602

  Fly   535 ------------------NERSPSSVAHLDAQIKLIRVVANMSVNPEVGAGLGNVRSLGAVLLQL 581
                              |:.:..:|..:.|.::|:|...:..|...|...|.|:.|..||.:.:
Mouse   603 KNACGALRNLVFGKSTDENKIAMKNVGGIPALLRLLRKSIDAEVRELVTGVLWNLSSCDAVKMTI 667

  Fly   582 LSKTSEELTK------------------KKSPEQQELLHATLGALHNLCFYQDKQAAVQPLAEGS 628
            :......||.                  |...:...:|..|.|.|.||....::........||.
Mouse   668 IRDALSTLTNTVIVPHSGWNNSSFDDDHKIKFQTSLVLRNTTGCLRNLSSAGEEARKQMRSCEGL 732

  Fly   629 LQSLIDDLSASL------AKVLGNCQTSVT----KVEL----ARVLG 661
            :.||:..:...:      :|.:.||..::.    ::||    ||:||
Mouse   733 VDSLLYVIHTCVNTSDYDSKTVENCVCTLRNLSYRLELEVPQARLLG 779

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG32668	NP_727502.1	armadillo repeat	571..611	CDD:293788	10/57 (18%)
		armadillo repeat	619..665	CDD:293788	13/57 (23%)
		armadillo repeat	670..708	CDD:293788
Pkp4	XP_036016888.1	DUF5585	71..>357	CDD:465521	46/266 (17%)
		armadillo repeat	545..570	CDD:293788	6/25 (24%)
		Arm	574..613	CDD:425727	6/38 (16%)
		armadillo repeat	578..614	CDD:293788	4/35 (11%)
		ARM	618..659	CDD:214547	9/40 (23%)
		armadillo repeat	622..657	CDD:293788	7/34 (21%)
		armadillo repeat	664..715	CDD:293788	7/50 (14%)
		armadillo repeat	723..764	CDD:293788	7/40 (18%)
		armadillo repeat	840..870	CDD:293788
		PLN03200	863..>984	CDD:215629
		ARM	880..915	CDD:214547
		armadillo repeat	882..914	CDD:293788
		armadillo repeat	921..962	CDD:293788
		ARM	964..1008	CDD:214547
		armadillo repeat	968..1003	CDD:293788