Protein Alignment CG32668 and Armc2

DIOPT Version :10

• Sequence 1: NP_727502.1
• Gene: CG32668 / 318147
• FlyBaseID: FBgn0052668
• Length: 863
• Species: Drosophila melanogaster
• Sequence 2: NP_001030030.2
• Gene: Armc2 / 213402
• MGIID: 1916449
• Length: 854
• Species: Mus musculus
• Alignment Length: 963
• Identity: 239/963 - (24%)
• Similarity: 381/963 - (39%)
• Gaps: 299/963 - (31%)

  Fly    51 ASEQSLNKLGLVSSGTSGMGRRKTSAELISEAKMFLGESVNAVPLLATGGARLVSTRRPITPRES 115
            :::|.|.||.  |.....:.:::||||:||||:       ||:        |.|.|:||.||||.
Mouse     4 SNDQKLEKLD--SFYRPPVSKQRTSAEIISEAR-------NAL--------RTVRTQRPFTPRED 51

  Fly   116 GRVLYGKVAL---AGRPPSAFSMR----YLQNEKPST---------------------------- 145
            .|.|:|..:.   ..||||:||:.    .|.:.||.:
Mouse    52 QRKLFGPASSRSPENRPPSSFSLHASSFELSDSKPISGTRLRPLELKPKAPASPGTEDACLSFPK 116

  Fly   146 ----PRQLPALSGS----------------------------VSATPMPT------RNGA----- 167
                |.::..:||:                            .|:.|:..      |||.
Mouse   117 APLDPAKIRKISGARARFYRAASQGMLLPDRSPPAAHSKTVDESSKPVSVGSSTARRNGTHLTAS 181

  Fly   168 -----------LLC----QSSTETLIELL----------KQHSGLKDC----------------- 190
                       |.|    |.:||..:.||          |:.:....|
Mouse   182 SATGQLKSPPLLTCDQGFQETTEQEVSLLSQLRRGGDPGKRRARASSCPSSSDLSRKETRAASRA 246

  Fly   191 ----------------------------SDETVQHINAILQELY---TRVRKQERNYK-RGFILG 223
                                        ::|.::.:.|...:|:   ...|...:.:| |..:|.
Mouse   247 SSQEQETDTEVDEVFWKARIVPILHELENEEDIEEMCAACTQLHRTLEEARMLGKKFKRRTVLLK 311

  Fly   224 GLYGLVECTSPRVLLAVARVVLALRVTGSNLTGACKLIFKVARHEQHDALFHEHDVLELLIDGLG 288
            .||.||:..|..:.|.:|:::|||:|:|.||...||||||::|:|::|.|..|.::||.|::.|.
Mouse   312 ALYKLVDADSDPLSLKLAKLILALKVSGKNLLNVCKLIFKISRNEKNDTLMQEDNILESLLEVLR 376

  Fly   289 HASPLDEPEACIYAYGCIRFLTASSAQERDDALNRNWIGLETSGESQSLPIPALMPPALSAISTS 353
            ........||.:|..|.::|::.|
Mouse   377 AEELQSNTEAFLYCMGALKFVSGS----------------------------------------- 400

  Fly   354 LCPRKLTGQQTLVSRLARHGAVELMILHLQMLNEAGATKRLQGPPL----HTLYQLSAAMRALAD 414
              |..||       .:...||||::   .|::.|........|..|    |.|.|.:|.:|.|.|
Mouse   401 --PGFLT-------EMVNKGAVEIL---AQLIKEMTEDTEKHGVCLPDSGHLLVQTTATLRNLVD 453

  Fly   415 VSQQQQRLQLQLQL-ACPHLIRAAEVSMGELEVQANVVRTLSVLSEDSDCCETLHNYAARIGLLL 478
            ....:.:|   |.: |.|||....|....:.::..|:.|..|.|:...|||..|.:|:....|.|
Mouse   454 SPLTRSKL---LNMGAFPHLCTVMEQHADDKDICTNIARIFSKLTSYRDCCAALASYSRCYALFL 515

  Fly   479 GPSCAGGGQWSERLLAVLSRLGYMLGNILAKHESARIQYFHNDVAMEYLLNVLE----------- 532
              |.....|.::.|:.   |:.::|||:.||...||..:.....::|.||.:.:
Mouse   516 --SLLNKYQKNQDLVI---RIVFILGNLTAKSNQARELFSRETGSVETLLTLFQSFYHHKENSPK 575

  Fly   533 -QLNERSPSSVAHLDAQIKLIRVVANMSVNPEVGAGL-GNVRSLGAVLLQLLSKTSEELTKKKSP 595
             ||:|..|.:.|. |..:||.||:||::::|.:|..| .|.|.:|.:|..|.||:..:.
Mouse   576 LQLSEAKPQAEAE-DVLVKLTRVLANIAIHPRIGPVLAANPRVVGLLLRTLESKSLGDC------ 633

  Fly   596 EQQELLHATLGALHNLCFYQDKQAAVQP----LAEGSLQSLIDDLSASLAKVLGNCQTSVTKVEL 656
              :||:..|:.|::||.|||.|.:.:|.    :||..|:.|:   |.::.::|          |.
Mouse   634 --EELVINTIAAINNLSFYQVKSSVLQHRKLYVAELLLRLLV---SNNMERIL----------EA 683

  Fly   657 ARVLGNLTRNEQARRCFCAAGGLPLMVQQLTKQAAGQDYELRTCAIGVLVNLLGDGEQRGPFLQL 721
            .||.|||:::...............|:..|  :|..||.....|  |||:||..|.|:|....:.
Mouse   684 VRVFGNLSQDHDVCNFLMQKNVHKFMITLL--EAKHQDICFSAC--GVLLNLTVDKEKRAILKEG 744

  Fly   722 RGAELLSLLLRGSLEQEDWFLANIVCQALWNLLIDGHCAANLCQSSNILDEVSDLLADYLDEDRL 786
            .|.:.|...|| .....||.||.:||:.||| ..:....|:.|...::.:.:..||:.:|||:..
Mouse   745 GGIKKLVDCLR-DFGPSDWQLACLVCKTLWN-FSENITNASECFGDDVANTLLILLSTFLDEELA 807

  Fly   787 SPGDDDNDNDEDDPEREAEDLDASDTDPEAHDALWE-DFALVATDLLERIQNN 838
            ..|..|            :||::      .|...|| :|..||..||:|||::
Mouse   808 LNGSFD------------QDLES------YHRLHWETEFKPVAQQLLQRIQSH 842

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG32668	NP_727502.1	armadillo repeat	571..611	CDD:293788	10/39 (26%)
		armadillo repeat	619..665	CDD:293788	13/49 (27%)
		armadillo repeat	670..708	CDD:293788	9/37 (24%)
Armc2	NP_001030030.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..116		36/128 (28%)
		PHA03247	<17..192	CDD:223021	39/189 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	140..194		5/53 (9%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	206..255		4/48 (8%)
		ARM 1	255..294		3/38 (8%)
		ARM 2	298..337		13/38 (34%)
		KAP	<343..573	CDD:253396	71/290 (24%)
		ARM 3	356..396		12/39 (31%)
		ARM 4	401..442		12/50 (24%)
		ARM 5	455..496		11/43 (26%)
		ARM 6	499..540		14/45 (31%)
		ARM 7	544..583		8/38 (21%)
		ARM 8	585..605		8/20 (40%)
		ARM 9	606..649		15/50 (30%)
		armadillo repeat	615..647	CDD:293788	10/39 (26%)
		ARM 10	651..692		15/53 (28%)
		armadillo repeat	693..733	CDD:293788	11/43 (26%)
		ARM 11	694..733		11/42 (26%)
		ARM 12	735..777		15/43 (35%)
		armadillo repeat	738..774	CDD:293788	12/36 (33%)