Protein Alignment CG32668 and Ctnnd2

DIOPT Version :10

• Sequence 1: NP_727502.1
• Gene: CG32668 / 318147
• FlyBaseID: FBgn0052668
• Length: 863
• Species: Drosophila melanogaster
• Sequence 2: NP_032755.2
• Gene: Ctnnd2 / 18163
• MGIID: 1195966
• Length: 1246
• Species: Mus musculus
• Alignment Length: 758
• Identity: 146/758 - (19%)
• Similarity: 227/758 - (29%)
• Gaps: 286/758 - (37%)

  Fly    26 PADSDKSDRQQQLAKHHQMRHHQPH------ASEQSLNKLGLVSSGTSGMGRRKTSAELISEAKM 84
            |.|...|:|...|::.....:.:|.      ||..|...|.|..:..|.:..|.|.|..
Mouse   138 PQDYSTSERPSLLSQSALQLNSKPEGSFQYPASYHSNQTLALGDTAPSQLPARSTQARA------ 196

  Fly    85 FLGESVNAVPLLATGGARLVSTRRPI----TPRESGRVLYGKV-ALAGRPPSAFSMRYLQNEKPS 144
             .|:|.:..   .||.|..::...|.    .|||......|.. .|...||:|.::.|..:..|:
Mouse   197 -AGQSFSQG---TTGRAGHLAGSEPAPPPPPPREPFAPSLGSAFHLPDAPPAAAALYYSSSTLPA 257

  Fly   145 TPRQLPALS------------------GSVSATP---MPTRNGALLCQS-STETLIELLKQHSGL 187
            .||....|:                  |:..|.|   .|.::.:.|.:| ||.:.|.::...:||
Mouse   258 PPRGGSPLTTTQGGSPTKLQRGGSAPEGAAYAAPRGSSPKQSPSRLAKSYSTSSPINIVVSSAGL 322

  Fly   188 ---KDCSDETVQHI--NAILQELYTRVRKQERNYKRGFILGGLYGLVECTSPRV----------- 236
               :..|..|||..  ::.:.:|.:.:              |.|..:..|...|
Mouse   323 SPIRVTSPPTVQSTISSSPIHQLSSTI--------------GTYATLSPTKRLVHASEQYSKHSQ 373

  Fly   237 -LLAVARVVLALRVTGSNLTGACKLIFKVARHEQHDALFHEHDVLELLIDGLGHASPLDEPEACI 300
             |.|.|    .|:..||...|:     :.:...||..|..|   |..|.....|..|:.|..  :
Mouse   374 ELYATA----TLQRPGSLAAGS-----RASYSSQHGHLAPE---LRALQSPEHHIDPIYEDR--V 424

  Fly   301 YAYGCIRFLTASSAQERDDALNRNWIGLETSGESQSLPIPALMPPALSAISTSLCPR-------- 357
            |....:|.|:                      :||..|:|   |.......||..|.
Mouse   425 YQKPPMRSLS----------------------QSQGDPLP---PAHTGTFRTSTAPSSPGVDSVP 464

  Fly   358 -KLTGQQTLVSRLARHGAVELMILHLQMLNEAGATKRLQGPPLHTLYQLSAAMRALADVSQQQQR 421
             :.||.|        ||.          .|.|.|          |..:.|.|....::.:...::
Mouse   465 LQRTGSQ--------HGP----------QNAAAA----------TFQRASYAAGPASNYADPYRQ 501

  Fly   422 LQLQLQLACPHLIRAAEVSMGELEVQANVVRTLSVLSEDSDCCETLHNYAARIGLLLGPSCAGGG 486
            ||....:..|:     ..|...|..:..:.|:.|:.|...|                 |...|
Mouse   502 LQYCASVDSPY-----SKSGPALPPEGTLARSPSIDSIQKD-----------------PREFG-- 542

  Fly   487 QWSERLLAVLSRLGYMLGNILAKHESARIQYFHNDVAMEYLLNVLEQLNERSPSSVAHLDAQIKL 551
             |.:                                  ..|..|::.|..:.||
Mouse   543 -WRD----------------------------------PELPEVIQMLQHQFPS----------- 561

  Fly   552 IRVVANMSVNPEVGAGLGNVRSLGAVLLQLLSKTSEELTKKKSPEQQELLHATLGALHNLCFYQD 616
                               |:|..|..||                             :|||..:
Mouse   562 -------------------VQSNAAAYLQ-----------------------------HLCFGDN 578

  Fly   617 K-QAAVQPLAEGSLQSLIDDLSASLAKVLGNCQTSVTKVELARVLGNLT---RNEQARRCFCAAG 677
            | :|.::  .:|.:|.|:|        :|.:..|.|.: .....|.||.   .|:..:......|
Mouse   579 KIKAEIR--RQGGIQLLVD--------LLDHRMTEVHR-SACGALRNLVYGKANDDNKIALKNCG 632

  Fly   678 GLPLMVQQLTKQAAGQDYELRTCAIGVLVNLLGDGEQRGPFLQ 720
            |:|.:|:.|.|..   |.|:|....|||.||......:.|.:|
Mouse   633 GIPALVRLLRKTT---DLEIRELVTGVLWNLSSCDALKMPIIQ 672

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG32668	NP_727502.1	armadillo repeat	571..611	CDD:293788	5/39 (13%)
		armadillo repeat	619..665	CDD:293788	11/48 (23%)
		armadillo repeat	670..708	CDD:293788	12/37 (32%)
Ctnnd2	NP_032755.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..50
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	133..237		25/108 (23%)
		PHA03247	<136..543	CDD:223021	103/520 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	255..308		10/52 (19%)
		ARM 1	390..432		11/51 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	428..479		16/93 (17%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	513..532		4/18 (22%)
		ARM 2	536..575		15/151 (10%)
		PLN03200	546..>719	CDD:215629	42/200 (21%)
		armadillo repeat	548..573	CDD:293788	10/83 (12%)
		ARM	577..617	CDD:214547	12/50 (24%)
		ARM 3	578..617		12/49 (24%)
		armadillo repeat	581..617	CDD:293788	11/46 (24%)
		ARM	621..662	CDD:214547	15/43 (35%)
		ARM 4	622..662		14/42 (33%)
		armadillo repeat	625..660	CDD:293788	12/37 (32%)
		armadillo repeat	667..718	CDD:293788	2/6 (33%)
		ARM 5	678..720
		ARM 6	724..769
		Arm	830..871	CDD:425727
		ARM 7	831..871
		armadillo repeat	834..871	CDD:293788
		ARM 8	903..942
		ARM	906..941	CDD:214547
		armadillo repeat	906..940	CDD:293788
		armadillo repeat	947..993	CDD:293788
		ARM	995..1039	CDD:214547
		ARM 9	996..1039
		armadillo repeat	999..1034	CDD:293788
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1063..1130
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1151..1175