DRSC/TRiP Functional Genomics Resources

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Protein Alignment Mur11Da and Mmp2

DIOPT Version :9

Sequence 1:NP_727652.3 Gene:Mur11Da / 318139 FlyBaseID:FBgn0052644 Length:626 Species:Drosophila melanogaster
Sequence 2:NP_112316.2 Gene:Mmp2 / 81686 RGDID:621316 Length:662 Species:Rattus norvegicus


Alignment Length:271 Identity:49/271 - (18%)
Similarity:70/271 - (25%) Gaps:106/271 - (39%)


- Green bases have known domain annotations that are detailed below.


  Fly    13 ALTLSQGHGDDY-LRFPDPGNIPRYNQ-----RPCGPRVCG---------KSGHCYRSFESICDF 62
            ||....|:||.. .:||.......||.     |..|.|.||         |.|.|..:..|....
  Rat   278 ALFTMGGNGDGQPCKFPFRFQGTSYNSCTTEGRTDGYRWCGTTEDYDRDKKYGFCPETAMSTVGG 342

  Fly    63 NDYNLKMIFS----GQELFELTE------PIYCQ--------------PSPPRTKLVDVGYYFNH 103
            |......:|.    |.:....|.      .::|.              |....:..:...:.|.|
  Rat   343 NSEGAPCVFPFTFLGNKYESCTSAGRSDGKVWCATTTNYDDDRKWGFCPDQGYSLFLVAAHEFGH 407

  Fly   104 RSLLVAQSQPSAYSSPIPRPSFTQNPKNIEHYDAYPSSDSYGPVQDYEL-----PYP-------- 155
            ...|.....|.|..:||  .::|:|.: :.:.|.....:.|||..|.:.     |.|        
  Rat   408 AMGLEHSQDPGALMAPI--YTYTKNFR-LSNDDIKGIQELYGPSPDADTDTGTGPTPTLGPVTPE 469

  Fly   156 -------------------------VWAFKRPQAPPRSP--------------PVSYRPP----- 176
                                     :|....|:..|..|              ...|..|     
  Rat   470 ICKQDIVFDGIAQIRGEIFFFKDRFIWRTVTPRDKPTGPLLVATFWPELPEKIDAVYEAPQEEKA 534

  Fly   177 -------YWYY 180
                   ||.|
  Rat   535 VFFAGNEYWVY 545

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Mur11DaNP_727652.3 None
Mmp2NP_112316.2 PG_binding_1 <70..97 CDD:396175
Cysteine switch. /evidence=ECO:0000250 100..107
Collagenase-like 1 110..221
Peptidase_M10 118..446 CDD:395334 34/170 (20%)
Collagen-binding 222..396 24/117 (21%)
FN2 226..274 CDD:128373
FN2 284..332 CDD:128373 14/47 (30%)
FN2 342..390 CDD:128373 5/47 (11%)
Collagenase-like 2 397..467 16/72 (22%)
Required for inhibitor TIMP2 binding. /evidence=ECO:0000250 414..662 22/135 (16%)
HX 468..662 CDD:238046 9/78 (12%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1565
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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