DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Mur11Da and Mmp8

DIOPT Version :9

Sequence 1:	NP_727652.3	Gene:	Mur11Da / 318139	FlyBaseID:	FBgn0052644	Length:	626	Species:	Drosophila melanogaster
Sequence 2:	NP_071557.1	Gene:	Mmp8 / 63849	RGDID:	631408	Length:	466	Species:	Rattus norvegicus

Alignment Length:	190	Identity:	39/190 - (20%)
Similarity:	55/190 - (28%)	Gaps:	43/190 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   176 PYWYYPTRRPEITKPCYGRTTTATKAPVTTT--------TTTEASTTTTTIEPSTSTNAAFTTTT 232
            |.|.:    ..:|......|...:||.|.|.        :.....|.|.|:|.....|.||.:..
  Rat   107 PKWTH----TNLTYRIINHTPQMSKAEVKTEIEKAFKIWSVPSTLTFTETLEGEADINIAFVSRD 167

  Fly   233 STEASTTTTTEGTTTSTEQ------------TTTTKTTSPSTSTEILTTTTE------LTTSTEP 279
            ..:.|......|......|            :..|.|.........|....|      |:.||:|
  Rat   168 HGDNSPFDGPNGILAHAFQPGRGIGGDAHFDSEETWTQDSKNYNLFLVAAHEFGHSLGLSHSTDP 232

  Fly   280 --------ARTTESTTTTIADSASTIT----EQSNTTEPTTTAEPTTTTEPTTTTEPTTT 327
                    |....||.:...|..:.|.    ...|..:||..:.| |..:|....:..||
  Rat   233 GALMYPNYAYREPSTYSLPQDDINGIQTIYGPSDNPVQPTGPSTP-TACDPHLRFDAATT 291

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mur11Da	NP_727652.3	None
Mmp8	NP_071557.1	PG_binding_1	32..87	CDD:279773
		Cysteine switch. /evidence=ECO:0000250	90..97
		Peptidase_M10	108..263	CDD:278824	30/158 (19%)
		ZnMc_MMP	108..263	CDD:239805	30/158 (19%)
		HX	277..465	CDD:238046	5/16 (31%)
		Hemopexin 1	277..326		5/16 (31%)
		Hemopexin 2	327..373
		Hemopexin 3	375..421
		Hemopexin 4	422..465
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1565
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900