DRSC/TRiP Functional Genomics Resources

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Protein Alignment Mur11Da and MMP12

DIOPT Version :9

Sequence 1:NP_727652.3 Gene:Mur11Da / 318139 FlyBaseID:FBgn0052644 Length:626 Species:Drosophila melanogaster
Sequence 2:NP_002417.2 Gene:MMP12 / 4321 HGNCID:7158 Length:470 Species:Homo sapiens


Alignment Length:245 Identity:47/245 - (19%)
Similarity:70/245 - (28%) Gaps:93/245 - (37%)


- Green bases have known domain annotations that are detailed below.


  Fly     9 VLLTAL-----TLSQGHGDDYLRFPDPGNIPRYNQRPCGPRVCGKSGHCYRSFESICDFNDYNLK 68
            :.|||:     :|..||..|    |.....|.|                     ...|.|.:.|.
Human   212 LFLTAVHEIGHSLGLGHSSD----PKAVMFPTY---------------------KYVDINTFRLS 251

  Fly    69 M--IFSGQELF------------ELTEPIYCQPSPPRTKLVDVG---YYFNHRSLLVAQSQPSAY 116
            .  |...|.|:            :.:||..|.|:.....:..||   ::|..|...:..|:    
Human   252 ADDIRGIQSLYGDPKENQRLPNPDNSEPALCDPNLSFDAVTTVGNKIFFFKDRFFWLKVSE---- 312

  Fly   117 SSPIPRPSFTQN---------PKNIE--------------HYDAYPSSDSYGPVQDYELPYPVWA 158
                 ||..:.|         |..||              ..|.|....:..|..:|  |..:.:
Human   313 -----RPKTSVNLISSLWPTLPSGIEAAYEIEARNQVFLFKDDKYWLISNLRPEPNY--PKSIHS 370

  Fly   159 FKRPQAPPRSPPVSYRP-----------PYWYYPTRRPEITKPCYGRTTT 197
            |..|....:.....:.|           .||.|..|| ::..|.|.:..|
Human   371 FGFPNFVKKIDAAVFNPRFYRTYFFVDNQYWRYDERR-QMMDPGYPKLIT 419

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Mur11DaNP_727652.3 None
MMP12NP_002417.2 PG_binding_1 28..87 CDD:307564
Cysteine switch. /evidence=ECO:0000250 90..97
Peptidase_M10 109..263 CDD:306839 16/75 (21%)
HX 279..470 CDD:238046 30/153 (20%)
Hemopexin 1 279..328 11/57 (19%)
Hemopexin 2 329..375 9/47 (19%)
Hemopexin 3 377..425 9/44 (20%)
Hemopexin 4 426..470
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1565
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

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